Aug 2026· Cell Biochemistry and Biophysics· Vol 84, pp. 4495 - 4522· 0 citations· 49 references
Medicine
TL;DR
This study identified five lung cancer-associated hub genes and provided preliminary evidence that resveratrol may modulate their expression, and provides a multi-level molecular framework for further investigation of resveratrol-responsive networks in lung cancer.
The findings of the current study offer that FN1, DPP4, CD36, KIT, ITGA2 and hsa-miR-124-3p may be novel biosignatures and therapeutic targets for PTC.
Mehdi Koushki, M. Farahani, Nasrin Amiri-Dashatan et al.· Journal of Genetic Engineeri...· 0 citations
Integrative analysis identifies VIM, SNAI1, ZEB1, and FN1 as a candidate EMT-associated hub signature linked with NPC progression, prognosis, and drug response patterns, suggesting that this EMT hub network may have potential value as a prognostic biomarker panel and as a putative therapeutic vulnerability requiring fu...
Xiao-Peng Sun, Bo Kou· Naunyn-Schmiedeberg's Archiv...· 0 citations
The TFAP4-CDK1 axis is established as a critical driver of malignant progression in CRC and Targeting this pathway could lead to the development of novel interventions for CRC.
Song Zheng, Lei Meng, Xiaoye Fan et al.· Journal of Molecular Histolo...· 0 citations
The results indicate that METTL9 may contribute to LUAD progression and EMT, potentially in relation to the TGF-β/Smad signaling pathway, potentially in relation to the TGF-β/Smad signaling pathway.
Chen Gong, Yu-Yan Chen, Yuchen Xie et al.· Frontiers in Bioscience· 0 citations
Integrated bioinformatics analysis identified TGFA, DDIT4, and SOX9 as candidate genes associated with EGFR-TKI resistance in EGFR-mutant lung adenocarcinoma, providing a basis for further investigation of resistance-associated biomarkers.
M. A. Hanif, Fadilah, N. Sutandyo et al.· BioMedInformatics· 0 citations
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