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GraESM-FuseDTA: adaptive gated multimodal fusion of graph neural networks and protein language models for robust drug-target affinity prediction.

Jun-Wen He
Aug 2026 · Naunyn-Schmiedeberg's Archives of Pharmacology · 0 citations · 22 references
Medicine

TL;DR

Experiments show that GraESM-FuseDTA achieves competitive overall performance and consistent advantages in ranking-oriented and variance-explanation metrics across warm start, drug cold start, target cold start, and strict pair cold start settings.

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