Bacteremia Due to Bacillus clausii ( Alkalihalobacillus clausii ): An Emerging Concern—Report of Two Cases

Comamonas testosteroni bacteremia and nosocomial polymicrobial infection following a prolonged hospital stay: A case report

Antibiotic Therapy in Acute Infectious Diarrhea and Clostridioides difficile Infection: Clinical Indications, Antimicrobial Stewardship, and Evidence Gaps

Background: Most acute gastrointestinal infections are self-limiting, but antibiotics remain essential for selected patients with severe, invasive, or high-risk disease. This narrative review examines when antibiotics should be started or withheld in adults and children with suspected or confirmed bacterial gastrointes...

Clinical Evidence in Respiratory and Urinary Tract Infections: Focus on Ceftibuten

Abstract Background Antimicrobial resistance (AMR) is one of the most pressing global health problems, resulting from the misuse and overuse of antibiotics across various sectors, which has led to the emergence and spread of resistant microorganisms. AMR occurs when microorganisms no longer respond to antibiotics. In I...

Effectiveness and Tolerability of Ceftriaxone–Sulbactam–Ethylenediaminetetraacetic Acid in the Treatment of Urinary Tract Infections: A Single-center Retrospective Study

Urinary tract infections (UTIs) are among the most common bacterial infections and are increasingly complicated by rising antimicrobial resistance, particularly among Gram-negative uropathogens. Ceftriaxone–sulbactam–ethylenediaminetetraacetic acid (CSE) is a combination designed to enhance activity against resis...

Ceftobiprole in the Management of Severe Legionella pneumophila Pneumonia in Critically Ill Patients: Two Illustrative Case Reports

Legionella pneumophila is a pathogen responsible for severe ‘atypical pneumonia’ and is often associated with high mortality rates in hospitalized patients. Atypical pneumonia can progress to severe forms with fatal outcomes, causing multi-organ damage. The standard of care involves antibiotics such as fluoroquinolones...

The Clinical Significance of Streptococcus mitis Bacteremia

Abstract Background Except for their role in bacterial endocarditis, nonpneumococcal Streptococcus mitis group (SMG) bacteria have traditionally been regarded as commensals of the oropharynx. Widespread adoption of matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry has increased id...