Findings support RAG as a promising approach to improve the accuracy, consistency and safety of LLM-driven DMHIs through a controlled comparison of RAG-enabled versus RAG-disabled modes.
Abstract
Digital mental health interventions (DMHIs) offer scalable support, but ensuring they accurately detect users'intent during volatile situations can be challenging. Pure parametric Large Language models (LLMs) do not contain specific safety critical architecture, and can miss critical cues, or hallucinate, undermining reliability. Retrieval Augmented Generation (RAG), which supplements an LLM with retrieved context, could enhance intent detection during volatile situations. Commercially available DMHIs typically combine multiple independent safety layers like rule-based filters, symbolic escalation protocols, and neural classification. The incremental contribution of any single layer, however, remains unquantified. This paper evaluates six LLM models within a DMHI called Wysa, via a controlled comparison of RAG-enabled versus RAG-disabled modes. Anonymized real and synthetic user-chatbot exchanges were annotated by a qualified clinical team against multi-class intent categories (e.g. self-harm, abuse, panic). The study computed classification accuracy, recall, precision and F1 scores against ground truth labels and tested differences for statistical significance. Performance was also examined by risk category and inter-model agreement. While RAG caused a rise in false alarms, the trade-off is consistent with safety-critical design principles that prioritize sensitivity, where flagged cases are routed to additional review rather than acted on directly. Overall, these findings support RAG as a promising approach to improve the accuracy, consistency and safety of LLM-driven DMHIs. Keywords: Digital Mental Health Intervention, Large Language Model, Retrieval Augmented Generation, Accuracy, Recall, Precision
Background/Objectives: Large language models (LLMs) show promise for clinical decision support, yet their accuracy in interpreting specialized medical guidelines remains uncertain. Retrieval-augmented generation (RAG) may enhance performance by grounding responses in authoritative knowledge bases. This study aimed to c...
Andreas Vollmer, Lara K. Schorn, Felix Schrader et al.· Diagnostics· 0 citations
Functional requirements for RAG systems serving cognitively diverse populations, including temporal user modelling that tracks cognitive trajectories over time, caregiver-in-the-loop retrieval that enables verification and oversight, consent-aware evidence access that respects fluctuating capacity, and cognitive-load-a...
Claire Rogers, Asmaa Z. A. M. Alqadri, Fiona A. Beaton et al.· Annual International ACM SIG...· 0 citations
This study implements a Retrieval-Augmentation Generation approach for automatic fact-checking of health claims using the PubHealth dataset, and compares its performance against a pure generative model.
ReFrame is a training-free multimodal input reframing framework where two agents share a lightweight locally deployed MLLM: the evidence-generation agent constructs complementary risk and utility evidence, and the rewrite-and-routing agent converts it into a safe proxy prompt and image-routing decision before calling t...
Wenzheng Jiang, Xuan-Kun Rong, Yuan-Zhao Zhai et al.· 0 citations
The proposed Retrieval-Augmented Large Language Model architecture for trustworthy conversational AI in diabetes care is presented, which combines clinical entity recognition, hybrid dense–sparse retrieval, patient-context filtering, cross-encoder reranking, evidence-constrained prompt construction, and multi-layer saf...
Muhammad Jamil, A. Kavak, Sema Bayraktar et al.· IEEE Access· 0 citations
It is suggested that multimodal safety cannot be enforced reliably without modeling the requested operation, the visual target to which it applies, and the confidence of that grounding.