DentAgent is introduced, an evidence-centric multi-agent framework, in which the Orchestrator coordinate five specialized agents spanning various modalities, which supports its value for broadly applicable and traceable multimodal dental reasoning, and highlights its potential as a technical foundation for population oral health assessment and management.
Abstract
Oral diseases affect billions of people worldwide, underscoring a pressing need for accurate and reliable dental assessment that integrates heterogeneous evidence from domain knowledge, radiographs, intraoral photographs, and 3D dental data. Most existing dental AI systems remain modality- or task-specific. Although recent vision-language models support flexible dental question answering, directly generated response leaves evidence implicit and untraceable. To address these limitations, we introduce DentAgent, an evidence-centric multi-agent framework, in which the Orchestrator coordinate five specialized agents spanning various modalities. Each specialist utilizes domain tools to convert observations into structured evidence records. The Evidence Blackboard manages these records as a shared evidence state, tracking coverage, gaps, and conflicts before response generation. This standardized evidence representation integrates isolated dental capabilities into a unified agentic workflow. Across four benchmarks, DentAgent demonstrates leading performance, even surpassing the senior specialists by 17.3 percentage points on multi-label diagnosis, which supports its value for broadly applicable and traceable multimodal dental reasoning, and highlights its potential as a technical foundation for population oral health assessment and management.
DentVLM is a dental vision-language model developed to support dental diagnosis across seven oral imaging modalities and 36 tasks that surpasses junior readers, matches intermediate general practitioners and approaches senior specialists, and reduces diagnostic time by 15.0-37.0% in collaborative clinical workflows.
Zijie Meng, Jinxiang Hao, Xi-Wei Dai et al.· Nature Communications· 1 citation
AgentEYE is an auditable multimodal agent that routes ocular images to specialized fundus and B-scan tools, retrieves guideline/web evidence, and synthesizes evidence-grounded reports that supports evidence grounding and citation auditability.
Kai-Kai Zhao, Qixuan Sun, Dao-Huan Kang et al.· Cell Reports Medicine· 0 citations
The results demonstrate the feasibility and potential value of agent-based orchestration for enabling adaptive, validated, and interpretable multimodal imaging workflows while providing a scalable foundation for complex multi-step clinical analysis.
Hoda Helmy, Chaima Ben Rabah, Ahmed Serag· Applied Informatics· 0 citations
EviDx is introduced, an evidence-aware active diagnosis framework that pairs patient-specific diagnostic environments with a clinical diagnostic scaffold and an observer-guided runtime harness that improves diagnostic performance and process stability while revealing model-dependent capability boundaries.
Sarse Multi-Stage Expert-Agent Routing is proposed, a language-based clinical reasoning framework that models diagnosis as a stage-wise routing process and adaptively activates a sparse set of medical expert agents, supported by expert-specific memory across stages.
Sike Xiang, Shuang Chen, Qianpeng Sun et al.· 1 citation
This study develops a collaborative framework in which several agents analyze a medical question from different professional perspectives, discuss the evidence, vote on the proposed answer, and revise unresolved questions up to three times, showing that structured collaboration can make medical artificial intelligence...
Xueyan Zhang, Xin Nie, Yuankun Liu et al.· Mathematics· 0 citations
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