This study systematically elucidates the dual inhibitory mechanisms of thermosonication against Bacillus subtilis spores through integrated transcriptomic-proteomic analysis, identifying critical genes at the regulatory level and clarifying indirect suppression through metabolic network disruption.
Temperature-dependent variations in the molecular characteristics of intact spores, including changes associated with Ca2+-dipicolinic acid, protein-related, and nucleic acid-related spectral features under different sporulation temperatures are revealed.
Mengya Li, Kequan Xing, Sun-Hee Wang et al.· Food Research International· 0 citations
Results showed that cdaA is critical for osmotic and ethanol tolerance but negatively modulates bile salt resistance in S. thermophilus, suggesting that absence of cdaA confers a survival advantage under bile salt stress.
Yizhou Fan, Xinxin Liu, Xin Song et al.· International Journal of Bio...· 0 citations
The results suggest that facing continuously increased environmental stress over time, GHZJ-1 undergoes global transcriptional reprogramming and resource reallocation, downregulating basal metabolism to construct a synergistic antagonistic system coupling chemical defense with nutritional competition.
Wen-Ji Chen, Yu Ni, Yuan-Yuan Bai et al.· Microorganisms· 0 citations
This study uncovers a previously unappreciated mechanism of Tps1-mediated heat adaptation in C. deneoformans, by revealing that Tps1 functions as a critical metabolic gatekeeper that safeguards glycolytic flux to sustain growth at elevated temperatures.
V. Yadav, Kahlia A. Carl, J. Heitman et al.· bioRxiv· 0 citations
This review highlights SpoVG’s function in Staphylococcus, including its regulation of the expression of the adhesion factor gene sasC and the thermonuclease, which enables SpoVG to act as a molecular rheostat that influences biofilm formation and reduces acute virulence in response to environmental signals.
Abirami Karthikeyan, A. Javaid, G. N. A. Charway et al.· World Journal of Microbiolog...· 0 citations
This work utilized an AlphaFold3-based structure-prediction approach to identify candidate genes and developed a Bt chassis strain that can be universally used to express new pesticidal proteins, providing a versatile framework for next-generation biocontrol and sustainable pest-management innovation.
Shi-Qing Li, Xin Zhang, Tinglu Yan et al.· Trends in Biotechnology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.