Comparison of long term results after percutanous coronary intervention in coronary bifurcation lesions using drug-eluding stents with durable or resorbable polymer

Abstract

Bioresorbable polymer drug eluding stents in coronary interventions have shown promising, yet mixed results in terms of outcome. The long-term results in case of bifurcation interventions remains largely unknown. The goal of this study is to elucidate the long-term outcome of usage of bioresorbable polymer stents versus durable stents in a large volume center. We investigated 3991 patients in a large registry undergoing percutaneous coronary bifurcation intervention with a follow up time of three years. 17.9% of patients received bioresorbable polymer and 82.1% received durable polymer stents respectively. Primary endpoint was major adverse cardiac events (MACE) consisting of death, myocardial infarction, or target lesion re-intervention. Survival was analysed with Kaplan-Meier curves and proportional hazard models. MACE occurred in 20.7% of patients, which received bioresorbable polymer and in 24.5% of patients which received durable polymer stents respectively. Survival analysis has shown no statistical difference between the types of stents (log rank=0.013, P=0.909). Stenting of bioresorbable versus durable polymers in bifurcation lesions have shown no statistical difference after three years.Survival bio versus durable stentsFor image description, please refer to the figure legend and surrounding text.