Plant virus-derived siRNAs stay a step ahead of viral short-range spread.
Medicine
Abstract
Whether mobile virus-derived siRNAs can pre-immunize uninfected plant tissues has been a long-standing assumption in plant biology. In this issue, Albertini et al. demonstrate that they indeed establish an AGO1-dependent immune zone of adjacent uninfected short-range cells, and this mobile pre-immunization is impacted by viral suppressors of RNA silencing.