The Use of Antiparasitic Drugs and Preservatives in the Agro-Industrial Complex in Light of the Antibiotic Resistance Problem. Part 2

Abstract

In the agro-industrial complex (AIC), a group of relatively rare antimicrobial drugs is used in addition to medically critical antibiotics; they are not considered to have a significant impact on the problem of antibiotic resistance among pathogenic microorganisms. As is the case with growth stimulants and fungicides, certain types of antiparasitic antibiotics and insecticides, as well as food additives and preservatives, are recommended for use in the agricultural sector. These drugs differ from those used in medicine in terms of their mechanisms of action. They can act as inhibitors of the functions of cell membranes, growth factors, synthesis of the cell wall of bacteria and fungi, synthesis of nucleic acids, as well as disrupt cellular balance. The review notes that although the compounds under consideration do not pose an immediate threat to the development of antibiotic resistance of pathogenic microorganisms, the drugs based on these compounds can still affect the increase in the level of resistance of other microorganisms circulating in the environment.