Abstract C028: Health related quality of life status among Black prostate cancer survivors
Abstract
Globally, Black men suffer the greatest prostate cancer (CaP) burden. This study evaluated health-related quality of life (HRQOL) among Black prostate cancer survivors (CaPS) and compared their HRQOL by stage. We used a validation study to compare the HRQOL outcomes between the validation study and our sample. This study is part of a larger intervention program of research aimed at improving HRQOL. This investigation analyzed the baseline survey data. Data was collected via a self-report survey, including questions on demographic, medical history, comorbidities, Functional Assessment of Cancer Therapy-General (FACT-G) scale. Descriptive analyses and One-sample Tests were performed in STATA to identify outcomes and statistical significance. 138 CaPS completed the baseline survey. Most were over 55 years old (93.5%), US-born African American (90.6%), and diagnosed at stages1-3 at first diagnosis (63.8%). For the overall HRQOL status, CaPS reported good total FACT-G score (M=84.3, SD=17.8); the physical well-being subscale had the highest average score (M=24, SD=4.8), followed by functional well-being (M=20.5, SD=6.6), social well-being (M=19.9, SD=7.1), and emotional well-being (M=19.8, SD=3.9). We analyzed overall FACT-G HRQOL by stage and recoded stages 1 and 2 into local diseases (M=87.6, SD=16.1) and stage 3 as regional spread (M=67.5, SD=23.1). Compared to the validation study, for local diseases, our CaPS reported similar HRQOL (87.6 vs. 85.1). Our regional spread CaPS reported a significantly lower mean (67.5 vs. 87.9, p=0.0042). Although experiencing high CaP incidence and mortality, and poor survivorship care quality, HRQOL among Black CaPS is severely understudied. This study is one of the few to examine HRQOL using a standardized measure. We found early-stage CaPS reported good HRQOL; however, stage3 reported significantly poor HRQOL outcomes. The findings of this study reveal the urgent need to develop tailored interventions considering both demographics and medical conditions for improving overall HRQOL. The poor outcomes of our stage3 CaPS suggest survivors with more advanced diseases require greater attention with tailored interventions to reduce their burden and address their unique HRQOL needs. Kimlin T. Ashing, Floyd Willis, Christopher Williams, John McCall, Gaole Song, Liam Gima-Lange, Folakemi Odedina. Health related quality of life status among Black prostate cancer survivors [abstract]. In: Proceedings of the 19th AACR Conference on the Science of Cancer Health Disparities; 2026 Oct 18-21; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2026;35(10 Suppl):Abstract nr C028.