Extraction and Evaluation of Tridax Procumbensherbal Cream for Antimicrobial and Anti-Inflammatoty Activity

Abstract

The present study focuses on the extraction and evaluation of Tridax procumbens leaves for their antimicrobial and anti-inflammatory properties, with the goal of formulating a stable and effective herbal cream. Tridax procumbens, traditionally used in Ayurveda, is known for its rich content of bioactive compounds such as flavonoids, alkaloids, tannins, and terpenoids, which contribute to its therapeutic effects. In this project, both ethanolic and aqueous extracts of the plant were prepared and incorporated into a cream base. The formulated cream underwent physicochemical evaluation including pH, viscosity, and spreadability, along with biological screening for antimicrobial and anti-inflammatory activities. The antimicrobial efficacy was assessed using zone of inhibition methods against bacterial and fungal strains, while anti-inflammatory potential was evaluated through suitable laboratory tests. Results indicated that the ethanolic extract showed comparatively higher biological activity. The final formulation was found to be stable, safe, and effective, highlighting the potential of Tridax procumbens-based herbal cream as a natural alternative for the treatment of skin infections and inflammation.