TL;DR
The observed relationship between T3 and NOBOX suggests a possible thyroid-dependent mechanism affecting ovarian function and combined assessment of T3, TSH, prolactin, and NOBOX may improve the identification of women at risk of infertility.
Background: Endocrine dysfunctions, including disturbances in gonadotropins, thyroid hormones, and prolactin, are important contributors to female infertility and may adversely affect reproductive function and menstrual regularity. Objectives: To determine the prevalence of hypothyroidism and hyperprolactinemia, compar...
Thyroid autoantibody burden may be increased in euthyroid women with PCOS despite broadly similar thyroid hormone concentrations, despite broadly similar thyroid hormone concentrations.
Background: Ovarian malignancy develops within a complex endocrine environment, and alterations in reproductive hormones may reflect changes in ovarian function, reproductive aging, and tumor-related biology. However, the combined circulating profile of gonadotropins, progesterone (P4), and prolactin (PRL) in ovarian c...
Persistent metabolic abnormalities may occur in hypothyroid patients despite levothyroxine (LT4) therapy. This study evaluated serum retinol and retinol-binding protein (RBP) levels in LT4-treated hypothyroid patients and their association with thyroid function, disease severity, and autoimmunity. A cross-se...
Polycystic ovary syndrome (PCOS) is a complex endocrine–metabolic disorder defined by clinical and/or biochemical hyperandrogenism and ovulatory dysfunction and accompanied by chronic low-grade inflammation and altered adipokine and cytokine profiles. This study assessed interleukin-6 (IL-6) gene expression and its rel...
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