Chronic OP exposure, reflected by these indirect urinary biomarkers, is associated with increased mortality, with heightened vulnerability in younger adults, and underscore the need for stricter pesticide regulation and targeted public health interventions.
Residents of agricultural regions are exposed to complex mixtures of agricultural and household pesticides, yet determinants of exposure remain poorly characterized in low-and middle-income countries, limiting accurate exposure assessment and health risk evaluation. This study aimed to identify self-reported recent and...
Higher urinary DETP was associated with greater heart disease mortality in middle-aged and older adults, and in vitro experiments provided hypothesis-generating support—most directly for inflammatory signaling—rather than confirmation of the epidemiological pathway.
The need for integrated mitigation strategies that address both environmental exposure and nutritional vulnerability to reduce the health impacts of As among primary schoolchildren from As-affected and apparently control areas is highlighted.
The data do not support a robust county-level association between agricultural pesticide application and later PD mortality, and the apparent weak positive gradient is explained by geographic, demographic, and socioeconomic confounding.
BACKGROUND Studies have indicated that exposure to household pesticides is prevalent among the population. Nevertheless, the relationship and contributing factors linking urinary metabolites of household pesticides to circulating levels of sex steroid hormones in human serum remain insufficiently explored. OBJECTIVE...
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