Aug 2026· Zhonghua zhong liu za zhi [Chinese journal of oncology]· Vol 48 8, pp.
975-982
· 0 citations
Medicine
TL;DR
Pyridoxic acid suppressed HT-29 cell viability and migration, and correlated positively with several upregulated bacteria, suggesting a microbiota-metabolite axis underlying its anti-tumor effect.
New insights are provided into the biological effects of LFH on colon cancer and its potential application in the development of LFH-based functional foods are supported.
Han-Jun Jiang, Xue Deng, Jing Yang et al.· Food Science and Human Welln...· 0 citations
BRR shows significant promise in alleviating colitis-associated CRC through various mechanisms, including the modulation of gut microbiota, regulation of immune responses, and enhancement of intestinal barrier function.
Yalan Huang, Junhui Zhang, Huiqing Yu et al.· Molecular Nutrition & Food R...· 0 citations
The preliminary biological assessment suggests that the polysaccharide subfraction SM05 alleviated the symptoms of UC induced by DSS, and may be related to the activation of the Nrf2/Keap1 pathway, the inhibition of pyroptosis, and the regulation of the intestinal microbiota.
Qing Luo, Yangyang Xu, Zhihua Li et al.· Frontiers in Pharmacology· 0 citations
Lachnospiraceae bacterium biologics abstracts accession-2278 (BAA-2278) is associated with anti-CRC effects in preclinical models, potentially mediated through regulation of gut microbiota homeostasis and inhibition of Wnt/β-catenin signaling via its metabolite malate.
Ze-Jun Fang, Yan-Yan Hu, Min-Jing Zhu et al.· Frontiers in Bioscience· 0 citations
PUP alleviates MASH via a gut microbiota-BSH-BA-FXR axis by remodeling the gut microbiota, enhancing BSH-dependent BA metabolism, and restoring physiological FXR feedback signaling.
Wei Gao, Jie-Wen Shi, Li-Juan Xie et al.· Journal of Ethnopharmacology· 0 citations
It is suggested that processing, particularly with black bean decoction (PPM), can alleviate PM-induced hepatotoxicity by reshaping the GM, restoring its metabolic products (SCFAs), normalizing bile acid signaling, and downregulating the FXR/NF-κB inflammatory axis within the gut-liver axis.
Andong Dong, Yaya Bai, Yang Xiao et al.· Journal of Ethnopharmacology· 0 citations
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