Skip to content
Preprint

Being judged through the record: A Rosenhan-inspired test of psychiatric label sensitivity in large language models

Oct 2026 · 0 citations · 32 references
Computer Science

Abstract

The integration of large language models (LLMs) into clinical decision-making raises unresolved questions regarding diagnostic bias. We investigate whether a documented psychiatric history alters LLM recommendations when the current clinical evidence is identical. Using a counterfactual experiment inspired by Rosenhan's 1973 field study, we factorially varied diagnostic-history condition (no prior diagnosis stated vs. prior schizophrenia diagnosis) and current-evidence condition (voices ceased vs. voices persisted) within a clinical vignette. Across five LLMs (GPT-5.6 Sol, Claude Sonnet 5, Gemini 3.6 Flash, Grok 4.6, and Mistral Large 2512), we generated 20,000 model responses across independent queries. When evidence supported discharge, adding a prior schizophrenia diagnosis increased recommendations for continued hospitalization nearly fivefold, from 4.7% to 22.3% (risk difference, 17.5 percentage points; 95% CI, 16.2-18.8). This shift occurred across all five models (risk-difference range, 10.4-34.4 percentage points). In the same condition, reference concordance decreased from 95.3% to 77.7%, while stated decision confidence increased. Across all model-by-evidence contrasts, confidence increases corresponded to Cohen's d values of 0.35-1.09. Signal-detection analyses showed that the prior diagnosis shifted the decision criterion toward hospitalization across all five models and reduced discrimination between the two current-evidence conditions in three of them. When current evidence supported continued hospitalization, the label increased the recommendation for hospitalization from 92.6% to 97.0%.

View source

Similar papers

#artificial intelligence Review Oct 2026

PsyCIDRA: A Dual-Agent Framework for Psychiatric Interviewing and Diagnostic Reasoning

Large language models show promise in clinical reasoning, but psychiatric interviewing requires guiding an evolving conversation. Their ability to carry out this interactive assessment remains less studied. We present PsyCIDRA, a dual-agent framework linking free-form psychiatric interviewing with diagnostic reasoning...

Milad Mohammadi, Fatemeh Akrami Shamsabadi, Zahra Mohseni et al. · 0 citations
Review Open access Oct 2026

Large Language Models in Clinical Decision Support: A Critical Review of Progress, Limitations, and the Path Toward Sustainable Healthcare

Large language models such as GPT-4, Med-PaLM 2, and BioMedLM are being increasingly applied to clinical decision support tasks including diagnostic reasoning, clinical documentation, medical question answering, and patient-facing health communication, with several studies reporting performance comparable to trained cl...

M. Oloko-Oba, Ebenezer Esenogho, Kehinde D. Aruleba et al. · 0 citations
Preprint Oct 2026

Large language models are vulnerable to incidental information in clinical documentation and reasoning

Large language models (LLMs) are increasingly relied upon to support ambient documentation and clinical reasoning. Here we examine the impact of a failure mode shared between these two applications by assessing their sensitivity to information incidental to the patient encounter. In 576 patient-clinician dialogues, we...

K. Vishwanath, Brandon Ye, A. Alyakin et al. · 0 citations
#artificial intelligence Preprint Sep 2026

K-Bench: a clinically calibrated benchmark for evaluating large language models in high-risk mental health conversations

People increasingly use large language models (LLMs) for mental health support, yet their safety in evolving, high-risk conversations remains poorly characterised. We developed K-Bench, a clinician-calibrated, protected benchmark evaluating 125 model configurations representing 33 base models from 14 providers across a...

L. Vowels, M. Vowels, Shivali Sharma et al. · 0 citations
Open access Sep 2026

Language models reflect clinical evidence but fail to adapt it to patients

Models often produced evidence-consistent numbers but failed to adapt them to a case or act consistently with their own stated cutoff, so explicit inputs, calculations and complete rules substantially improved performance in controlled prompts.

S. He, J. Joseph, P. Safari et al. · 0 citations
#artificial intelligence Preprint Sep 2026

Structure vs. Chain-of-Thought: Evaluating LLM Criteria Extraction for Depression Severity

A large language model (LLM) can rate depression severity directly from a social media post, or mark which clinical criteria the post shows and let a simple rule turn the count into a label. The latter is easier to audit because a clinician can check each marked criterion. We compare these approaches on two Reddit corp...

Xin-Kai Chen · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.