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Equity Gaps in Sex, Racial, and Ethnic Inclusion in United States Heart Transplant Trials

Oct 2026 · Clinical Transplantation · Vol 40 · 0 citations · 27 references
Medicine

TL;DR

Heart transplantation (HT) remains the definitive therapy for select patients with end‐stage heart failure but the extent of sex, racial, and ethnic inclusion in U.S. HT clinical trials has not been systematically evaluated at the level of clinical trials.

Abstract

Heart transplantation (HT) remains the definitive therapy for select patients with end‐stage heart failure. Equitable representation in clinical trials is essential to ensure that evidence guiding HT practice is generalizable across populations. However, the extent of sex, racial, and ethnic inclusion in U.S. HT clinical trials has not been systematically evaluated at the level of clinical trials.

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