Oct 2026· Georgetown Medical Review· Vol 10· 0 citations· 29 references
TL;DR
The definition of race and ethnicity as sociodemographic factors increased significantly between the years 2010 and 2020, suggesting a shift in terminology without a corresponding increase in deeper contextual interpretation, and the need for nuanced discussions of race/ethnicity in biomedical research that prioritize social determinants and avoid biological essentialism.
Abstract
ABSTRACT
Racial and ethnic health disparities remain a pressing issue in the United States, especially as the country grows more diverse. How race and ethnicity are discussed in medical research can influence data interpretation and the application of findings. We evaluated the presentation of race and ethnicity in Georgetown University Medical Center and MedStar-affiliated scientific research articles published in the years 2010 and 2020, focusing on whether these factors were framed as social or biological constructs and how this framing may have changed over this decade.
We conducted a targeted literature search using MEDLINE and PsycINFO databases with predetermined racial and ethnic terms for 2010 and 2020. The initial search yielded 81 publications from 2010 and 222 from 2020. Of these, 54 from 2010 were eligible, and 163 from 2020 were eligible. Blinded reviewers independently scored each publication for the context of race or ethnicity mentions, explanations provided (biological, social, both, or none), and race or ethnicity identification method.
The definition of race and ethnicity as sociodemographic factors increased significantly between the years 2010 and 2020 (5.6% vs 31.9%, P<.001). However, this increase in sociodemographic labeling occurred alongside a decline in social or multifactorial explanations for differences in race/ethnicity (58.1% vs 43.9%) and a slight increase in biological framing (25.6% vs 28.6%), suggesting a shift in terminology without a corresponding increase in deeper contextual interpretation. Race was descriptively more often contextualized as biological (25.6% vs 28.6%), while social or multifactorial explanations decreased, though these changes were not statistically significant. No statistically significant change was observed in identification methods for race/ethnicity (P=.16), though self-identification declined from 80.4% to 66.4% while researcher-assigned race increased from 2.2% to 12.3% over the same period.
These findings emphasize the need for nuanced discussions of race/ethnicity in biomedical research that prioritize social determinants and avoid biological essentialism. These findings support the need for institutional guidelines to promote responsible research practices.
Race and ethnicity data are rarely reported in clinical trials underpinning the NCCN Testicular Cancer Guidelines, and the near absence of demographic reporting impedes assessment of representativeness and may obscure disparities in access and outcomes.
S. Sapkota, N. Shah, S. Motkur et al.· JCO Oncology Practice· 0 citations
OBJECTIVES
The methods used to ascertain and categorize race and ethnicity in clinical research influence study design and may influence the interpretation and comparability of findings between studies. Use of inconsistent approaches across the literature may contribute to heterogeneity of findings, with some methods s...
Teresa Semalulu, Melanie A. Anderson, Zayd Schafer et al.· Journal of Clinical Epidemio...· 0 citations
PURPOSE
Diversity among pediatric surgery trainees plays a critical role in shaping the future workforce and the quality of care delivered to children. This study presents the first comprehensive analysis of all pediatric surgery graduates in the U.S. and Canada, evaluating racial and ethnic representation over time an...
Andreina Giron, Raquel González, Colin A. Martin et al.· Journal of Pediatric Surgery· 0 citations
BACKGROUND
Diverse representation in clinical research is essential for equitable healthcare. Despite mandates from organizations like the NIH and ICMJE, race and gender remain underreported in surgical research, raising concerns about the generalizability of findings. This study examines demographic reporting trends i...
Amber Chen-Goodspeed, Victoria Ende, Xiao-Yue Ma et al.· Surgical Endoscopy· 0 citations
INTRODUCTION
Accurate and complete measurement of race and ethnicity is essential in clinical research and practice, but it is often undermined by inconsistent definitions and flawed data sources. Electronic health records (EHRs) regularly contain race and ethnicity information, yet some studies reveal errors, particul...
Lillie D. Williamson, Hailie C. Hayes, Peter-Jon Williams et al.· Journal of the American Boar...· 0 citations
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