Review
Open access
An integrative review of APOL1 kidney disease with a focus on the Brazilian population
C. M. D. de Souza
B. S. de Oliveira Fam
G. C. Giudicelli
P. D. M. de Menezes Neves
F. V. Veronese
Fernanda S. Luiz Vianna
Medicine
Abstract
Highlights • CKD remains a major health burden in Latin America and middle-income regions.• APOL1 kidney disease poses diagnostic and therapeutic challenges in admixed populations.• Studies on APOL1 kidney disease are scarce in admixed and Afro-Brazilians.• Findings support new public health strategies for Afro-Brazilian and admixed populations.