Different patterns of spontaneous brain activity associated with cognitive impairment in SCA3 are revealed, providing novel imaging evidence for the pathophysiological mechanisms underlying cognitive decline in these patients.
Due to the psychotropic properties of kratom (Mitragyna speciosa), further studies are needed to measure its neurobiological impacts. This exploratory study employed resting-state functional magnetic resonance imaging (rs-fMRI) to examine alterations in brain activity and functional connectivity (FC) among kratom users...
Suzana Mat Isa, A. A. Abd Hamid, Muhamad Zabidi Ahmad et al.· Journal of Psychoactive Drug...· 0 citations
ABSTRACT Background Cognitive impairment is a prevalent and debilitating feature in multiple sclerosis (MS), yet its pathophysiology remains incompletely understood. Dysfunction of the neurovascular unit (NVU) and impaired neurovascular coupling (NVC) may be related to cognitive performance in MS, but this pathway rema...
Modulating FC between these hub brain regions (R-DLPFC and PCC) may provide new therapeutic strategies for cognitive recovery after DNICH and abnormal coordination of intra-network and inter-network FC of ECN and DMN may represent a shared neural mechanism of cognitive impairment after DNICH.
Xi-Wen Fan, Yu-Chen Lei, Yong-Bing Deng et al.· Frontiers in Neurology· 0 citations
The authors' multimodal findings suggest subregion- and laterality-specific alterations in the SN of patients with TLE, with patterns differing between RTLE and LTLE.
Xu Zhao, Huiting Wu, Si Jian et al.· BMC Medical Imaging· 0 citations
Previous studies have demonstrated widespread regional abnormalities in blood oxygen level-dependent (BOLD) amplitude of low frequency fluctuation (ALFF) in psychotic disorders. How regional ALFF is related to functional connectivity and behavior in psychotic illness, however, is poorly understood. Here we examined v...
J. Smucny, Korey P. Wylie, J. Tregellas et al.· Schizophrenia· 0 citations
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