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TL;DR
Young age at diagnosis of focal epilepsy, diagnosis of cortical dysplasia, MTS, and presence of complex partial seizures are risk factors for drug-resistant epilepsy.
OBJECTIVE Drug-resistant epilepsy (DRE) is associated with increased injury risk, cognitive decline, psychiatric illness, and premature death. Epilepsy surgery can be curative among well-selected individuals but remains underutilized. This study sought to identify people living with DRE in electronic health record (EHR...
OBJECTIVE To investigate the clinical features and risk factors for progression from acute-phase autoimmune encephalitis (AE) with epileptic seizures to autoimmune encephalitis-associated epilepsy (AEAE). METHODS We retrospectively analyzed clinical data from patients with acute-phase autoimmune encephalitis presenti...
BACKGROUND We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding. METHODS Individuals with CAE or JAE underwent both an...
OBJECTIVES Distinguishing Idiopathic Generalized Epilepsy (IGE) from focal epilepsy (FE) can be challenging when IGE cases present with asymmetric clinical or electroencephalographic (i.e., atypical) features. We aimed to identify factors that lead to discordance in IGE diagnoses among epileptologists. METHODS 41 pat...
Overall, the presence of SCSs alone was not associated with a poor outcome, but the spatial non-concordance with the seizure-onset zone was highly predictive for poor seizure outcome.
BACKGROUND Excess mortality has been demonstrated in individuals with epilepsy. Here, we aimed to examine mortality in patients from two independent First Seizure Clinics (FSCs), up to 20 years after a new epilepsy/unprovoked seizure diagnosis assigned by epileptologists. Patients were also grouped according to pre-exi...
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