Sep 2026· Journal of The American Geriatrics Society· 0 citations· 24 references
Medicine
TL;DR
Several patient-level factors present at time of admission are associated with prolonged hospitalizations for people living with dementia, and these findings can inform early identification and tailored interventions for those at risk.
Abstract
Background
People living with dementia (PLWD) are more likely to be hospitalized and have longer hospital stays compared with the general population. Prolonged hospitalizations are associated with inpatient complications, functional decline, and mortality. This study aimed to identify patient-level factors associated with prolonged hospitalizations for PLWD.
Methods
Secondary analysis of a stepped-wedge, cluster randomized trial that enrolled community-dwelling older adults hospitalized for at least 2 days at eight Veterans Health Administration hospitals between August 2017 and August 2019. A logistic regression model was used to identify patient-level factors associated with prolonged hospitalizations (≥ 21 days) for PLWD.
Results
2612 individuals with dementia were included in this cohort. PLWD had a median length of stay of 6.0 days (IQR: 4.0-9.0) and 138 (5.3%) were admitted to the hospital for at least 21 days. Social vulnerability (OR: 1.74, 95% CI: 1.16, 2.61), higher Nosos chronic disease burden (OR: 1.06, 95% CI: 1.01, 1.10), and presence of delirium at admission (OR: 1.55, 95% CI: 1.07, 2.26) were associated with higher odds of prolonged hospitalization. In contrast, greater clinical frailty was associated with lower odds of prolonged hospitalization (overall p = 0.006).
Conclusions
Several patient-level factors present at time of admission are associated with prolonged hospitalizations for PLWD. These findings can inform early identification and tailored interventions for those at risk. Further research is needed to better characterize these relationships, particularly frailty.
TRIAL REGISTRATION
NCT03300336.
OBJECTIVES
To examine whether the prognostic relevance of multimorbidity burden for hospital-associated disability (HAD) varies with baseline frailty in hospitalized older adults.
DESIGN
Retrospective multicenter cohort study.
SETTING AND PARTICIPANTS
We analyzed data from 1599 older adults aged ≥65 years admitted...
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IMPORTANCE
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INTRODUCTION
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High-risk HF patients could be identified at the time-of-diagnosis using routinely available clinical characteristics, enabling targeted interventions during critical periods to improve long-term outcomes.
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