Pan-cancer characterization of the pyrimidine catabolic enzyme UPB1 identifies a tumor-suppressive prognostic biomarker in skin cutaneous melanoma.

Yin Men Yi Shao Yong-Feng Chen Ping Wang Yiyang Li Zhen-Zhen Yang Rui-Ting Feng Hui Wang Yin-Sen Song Cong Ding

Jul 2026 · Naunyn-Schmiedeberg's Archives of Pharmacology · 0 citations · 39 references

Medicine

TL;DR

It is suggested that UPB1 functions as a tumor-suppressive factor linked to pyrimidine catabolism and may serve as a prognostic biomarker, particularly in skin cutaneous melanoma (SKCM).

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