Explore whether early-life physical and mental health and early family environments are associated with cognitive outcomes in later life using a life course approach.
Method
Using data from the Health and Retirement Study (N = 8213: baseline Mage = 67), we conducted a multivariable parametric survival analysis to evaluate how five domains of early-life disadvantage (low early-life SES, adverse parental behaviors, chronic diseases, early-life impairments, and early-life experiences) were associated with the timing of transition from normal cognition to impairment between 2006 and 2016.
Results
Over the study period, 52% of participants experienced a transition in cognitive status. Results showed that each additional indicator of low early-life SES and early-life impairment increased the risk of developing cognitive impairment. In contrast, early-life illness and early-life experiences were not associated with risk, and, unexpectedly, adverse parental behavior was linked to a decreased risk.
Conclusion
These findings underscore the importance of early-life conditions as predictors of later-life cognitive health and point to potential targets for future intervention research.
Among individuals who experienced family member deaths, losses occurring at younger ages were associated with higher risks of cognitive impairment than losses occurring at older ages, and there was no evidence of racial/ethnic or gender differences in these patterns.
Hyun-Hee Cha, Patricia A. Thomas, Christy L. Erving et al.· American Journal of Public H...· 0 citations
BACKGROUND
Late-life depression (LLD) is often accompanied by functional limitations, which may persist after symptomatic improvement, increasing relapse risk. Care for functional limitations in LLD is difficult, as they vary across different domains and are linked to both depression and aging. This study identified si...
K. Fredriksen, G. Lunansky, M. Huisman et al.· Journal of Affective Disorde...· 0 citations
Research shows that older Black Americans have increased risk for poor cognitive function in later life. In addition, they are also more likely to report experiencing early life adversity (ELA). However, there is limited research that examines the role of ELA on later life cognitive function among this population. Util...
Cleothia Frazier, Justin J. Hendricks· Journal of Racial and Ethnic...· 0 citations
Abstract Background Disability in old age is increasingly understood as a dynamic, reversible continuum rather than a static, permanent state, characterized by transitions between independence, compromised health, and functional limitation. Whether these transitions are impacted by the life-course history of depression...
F. Steffens, Y. Ma, F. Triolo et al.· European Journal of Public H...· 0 citations
OBJECTIVES
To examine whether adverse childhood experiences (ACEs) are associated with distinct multidimensional frailty patterns and transitions across frailty states in later life.
METHODS
We used harmonized longitudinal data from the English Longitudinal Study of Ageing, the Health and Retirement Study, and the Ch...
Zi-Han Wang, Fei Li, Ji-Yu Zhao et al.· Archives of gerontology and...· 0 citations
It is suggested that child loss has a persistent and graded negative association with HRQoL, with important variation by timing and gender, which highlights the need for targeted support and interventions to mitigate long-term health consequences among bereaved older adults.
Qing Su, Ke-Shan Liu· Quality of Life Research· 0 citations
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