Loganin Alleviates CCl4-Induced Acute Liver Injury by Promoting Mitophagy and Inhibiting NLRP3 Inflammasome

Yinchenhao Decoction Alleviates Liver Injury in CYP2D6-Induced Autoimmune Hepatitis Mice: An Integrated Transcriptomic and Proteomic Analysis.

Pentoxifylline mitigates CCl4-induced liver damage in rats: integrated biochemical, hematological, histopathological, and correlation heatmap analysis

It is suggested that PTX exerts significant hepatoprotective effects when administered after toxic insult, likely through modulation of oxidative stress and inflammation.

Remifentanil attenuates LPS-induced hepatic injury by modulating NRF2/HO-1 and necroptosis-related gene expression.

Remifentanil attenuated LPS-induced hepatic injury, and this effect was found to be associated with modulation of oxidative stress responses, inflammatory alterations, and necroptosis-related gene expression.

[Berberine attenuates necrotizing enterocolitis-associated brain injury via the TLR4/MyD88/NF-κB/NLRP3 pathway].

Anti-inflammatory and antioxidant effects of taxifolin against sepsis-induced renal injury in mice

Purpose: To investigate the effect of taxifolin in sepsis-induced renal injury.Methods: A total of 24 adult male Swiss albino mice were randomly and equally assigned to 4 groups (n = 6). Group 1 was the control (exposed to abdominal laparotomy without cecal ligation and puncture (CLP) procedure), group 2 underwent CLP...

Fucoidan Ameliorates Contrast-Induced Acute Kidney Injury in Mice by Modulating the TLR4/NF-κB and Nrf2/GPX4 Pathways

Objectives: The purpose of this study was to investigate the protective effects and underlying mechanisms of fucoidan on contrast-induced acute kidney injury (CI-AKI) in mice, focusing on the TLR4/NF-κB and Nrf2/GPX4 pathways. Methods: Five-week-old male ICR mice were randomly divided into normal control, contrast mode...