Cal calcium imaging of HVC projection neurons during freely produced songs is used to suggest that stable motor sequences need not rely on rigid repeated activation of the same cellular ensemble but can preserve temporal order while flexibly selecting which neurons contribute to each expression of the behavior.
During rhythm perception, accurate processing of temporal structure is essential for predicting when a stimulus will occur and for preparing appropriate actions. Subcortical circuits, particularly the cerebellum and basal ganglia, are known to play central roles in temporal processing, yet how neuronal activity in thes...
Masashi Kameda, Masaki Tanaka· Journal of Neuroscience· 0 citations
Flexible motor control requires that movements adapt to changing temporal contexts. Here, we test whether flexible timing is driven by context-dependent encoding across cortico-cerebellar circuits and how neural dynamics within these circuits enable accurate performance. To overcome the signal-to-noise limitations of c...
Coen S. Zandvoort, Charlotte C. Wissing, Jonathan Winter et al.· bioRxiv· 0 citations
The ventrointermediate nucleus of the thalamus (VIM) is implicated in motor sequence learning, yet the underlying neural mechanisms remain unclear. We recorded intracranial activity from the human VIM during a serial reaction time task to determine how neural dynamics support learning. Participants responded faster dur...
Angela Voegtle, L. Buentjen, Stefan Repplinger et al.· bioRxiv· 0 citations
Beta oscillations are a fundamental feature of brain activity, linked to long-range connectivity within canonical networks, inhibition of sensorimotor cortices and the maintenance of a stable sensorimotor state in situations where the external world is predictable. The importance of beta oscillations in brain function...
Joseph Gibson, Jessikah Fildes, Alan Kirby et al.· bioRxiv· 0 citations
The consolidation of novel motor skills has traditionally been investigated over the timescale of hours-days following practice. However, a growing body of evidence has demonstrated that consolidation of skills occurs more rapidly across a scale of seconds – a process termed ‘micro-consolidation’. Micro-consolidation o...
