Partner support and awareness were independently associated with maternal RSV vaccine acceptance, although partner awareness was substantially lower than pregnant women's awareness.
Abstract
Background
Maternal respiratory syncytial virus (RSV) vaccination was introduced into Japan's routine immunization program in April 2026. This study examined vaccine acceptance and household-level factors, including co-residing partner awareness and support, immediately before program introduction.
Methods
We conducted a nationwide web-based cross-sectional survey of pregnant women at 28-36 weeks of gestation and their co-residing partners from March 13 to 19, 2026. Paired data were obtained from 100 household pairs through the Rakuten Insight panel. The primary outcome was positive maternal RSV vaccine acceptance, defined as being vaccinated, planning vaccination, or intending vaccination. Associated factors were examined using logistic regression.
Results
Detailed awareness of the maternal RSV vaccine was higher among pregnant women than partners (66.0% vs. 22.0%). Among women with detailed awareness, 72.7% showed positive acceptance. Within-household agreement on detailed RSV and maternal RSV vaccine awareness was low (κ = 0.144 and κ = 0.220, respectively), with discordance mainly reflecting pregnant woman-only awareness. In multivariable analysis, partner support for vaccination (adjusted OR 11.17, 95% CI 3.66-34.07) and detailed partner awareness (adjusted OR 4.98, 95% CI 1.13-21.92) were independently associated with positive acceptance.
Conclusions
Partner support and awareness were independently associated with maternal RSV vaccine acceptance, although partner awareness was substantially lower than pregnant women's awareness. Implementation strategies should include co-residing partners as key participants in household decision-making.
BACKGROUND
Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants, particularly among vulnerable groups such as preterm newborns and infants with underlying medical conditions. The approval of the RSVpreF vaccine for use during pregnancy offers a new strategy for redu...
Mateusz Strózik, Hanna Wiciak, M. Socha et al.· Advances in Clinical and Exp...· 0 citations
Respiratory syncytial virus (RSV) is a leading cause of infant respiratory illness. In August 2023, the RSV protein-based vaccine (RSVpreF) became the first maternal vaccine approved in the United States to prevent RSV infection in newborns. The study aims to estimate RSVpreF vaccine uptake during its first RSV season...
Xiaofan Liu, J. Cloughesy, Tianzhou Yu et al.· Vaccine· 0 citations
Aim:
To assess the level of awareness and the factors associated with pregnant women’s decision-making regarding pertussis vaccination.
Materials and Methods
: A cross-sectional study was conducted using an online questionnaire to evaluate awareness, factors influencing willingness to receive vaccination durin...
E. Krieger, O. Samodova, T. R. Nizovtseva et al.· Journal Infectology· 0 citations
Adherence to the recommended complete vaccination schedule during pregnancy was low, particularly for the COVID-19 vaccine, except for COVID-19 and influenza.
M. Fortunato, A. C. Fernandes, Daniela Ferreira D'Agostini Marin et al.· Revista Brasileira de Saúde...· 0 citations
INTRODUCTION
The maternal pertussis vaccination (MPV) was introduced in the Netherlands at the end of 2019. Despite its effectiveness, vaccine hesitancy remains, possibly influenced by factors such as age, education, employment, parity, native language, and country of birth. This study investigates associations between...
Lisa van Vreeswijk-van Donselaar, Libertje Bosma, C. Zemouri et al.· Vaccine· 0 citations
Maternal influenza vaccination (MIV) is the most effective measure of preventing severe influenza-related complications in pregnant women. However, there is limited knowledge about MIV uptake in Kuwait. This study aimed to assess pregnant women’s knowledge, attitudes, and perceptions regarding MIV uptake and provis...
Fatemah Alhendyani, Louise Hayes, Laura Lindsey et al.· Scientific Reports· 0 citations
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