TL;DR
A late-term precipitous decline in PlGF identifies pregnancies at markedly elevated risk for preterm birth and neonatal morbidity, and provides important prognostic information beyond single time-point measurements.
BACKGROUND Preterm birth (PTB) is a leading cause of global neonatal mortality and long-term complications. Placental growth factor (PlGF) is a key regulator of placental vascular development; however, prospective evidence regarding the association between its first-trimester levels and the risk of PTB remains insuffic...
Objective: To evaluate the association between maternal angiogenic markers and neonatal outcomes in pregnancies with an estimated fetal weight (EFW) below the 10th percentile. Methods: This prospective study included 95 singleton pregnancies with EFW below the 10th percentile. Maternal serum placental growth factor (Pl...
Placental growth factor (PlGF) contributes to first-trimester screening algorithms for preeclampsia, but its prognostic performance as an isolated biomarker in routine Chinese care is uncertain. We performed a retrospective, single-centre cohort study among pregnancy episodes recorded in a hospital PlGF work...
Preterm preeclampsia (PE) is associated with significant maternal and neonatal morbidity, yet classifying patients at high versus low risk for acute adverse outcomes remains challenging. The objective of this study was to evaluate the relationship between placental growth factor (PlGF) and outcomes among patients wit...
Background Adverse pregnancy outcomes (APOs) increase the future risk of hypertension, but their impact on long-term postpartum blood pressure (BP) trajectories remains unclear. We aimed to characterize these trajectories and compare trajectory membership between women with and without APOs. Methods This community-base...
Introduction Maternal obesity is associated with altered maternal–fetal adipokine profiles and adverse early neonatal outcomes. This study aimed to characterize maternal and fetal adipokine patterns across obesity severity groups and to evaluate their associations with macrosomia and neonatal intensive care unit (NICU)...
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