Relationship between menopause and bone condition for dental implants: an integrative review

Abstract

ABSTRACT Menopause constitutes a physiological transition marked by significant hormonal fluctuations that substantially affect bone metabolism and may influence the predictability and outcomes of dental interventions, particularly implant therapy. This integrative review aims to critically examine the relationship between menopausal status and bone quality, alongside its implications for implant osseointegration. A systematic search of the PubMed, SciELO, Lilacs, and Scopus databases was conducted to retrieve studies published between 2015 and 2025. Studies investigating menopause, osteoporosis, bone metabolism, and dental implants were selected following rigorously defined inclusion and exclusion criteria. The cumulative evidence indicates that although menopause is associated with a decline in bone mineral density, implant-supported rehabilitation can achieve reliable and successful outcomes when treatments are predicated upon individualized treatment planning, comprehensive systemic evaluation, precise surgical execution, and coordinated interdisciplinary management. Thus, current evidence refutes the notion of menopause as an absolute contraindication for dental implant therapy. Instead, it advocates for meticulous systemic assessment and the adoption of tailored therapeutic strategies to enhance osseointegration and secure long-term implant success.