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Diagnosis of myocardial infarction in early presenters using 1-hour delta of high sensitive Troponin I: a pilot study

Jan 2026 · Clinics · Vol 81 · 0 citations · 34 references
Medicine

Abstract

Highlights • Early hscTrop I levels evaluated for NSTEMI diagnosis in non-CAD early presenters.• In this pilot study, a 1-hour absolute delta hs-cTnI of 4 ng/L showed 95% specificity for NSTEMI, though this finding requres validation.• Baseline hscTrop I < 3 ng/L achieved 86% NPV for ruling out early NSTEMI.• Delta hscTrop I was the strongest predictor with an AUC of 0.796.• Standard cut-offs may miss early NSTEMI in patients without prior heart disease.

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