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Bovine AAV - a promising vector for pulmonary gene therapy

Daniela C. Ivan Valérie Dubost L. Israel J. Weinmann Dennis Ungan Nina Carbonetti N. Stuber Magali Jivkov Esther Erard E. Biglieri Federica De Girardi Simon Mittermeier Maryam Syed B. Tigani Najwa Ouali-Alami Kristin Dreessen Colin Deniston Kannan Sankar Laura Bollepalli Vanessa Cornacchione E. Traggiai Dominique Brees A. Karle J. Carballido A. Cirillo
Jul 2026 · bioRxiv · 0 citations
Biology

TL;DR

Bovine AAV is position as a promising lung-tropic and immune-distinct vector for pulmonary gene therapy, with particular relevance for applications requiring systemic delivery in the presence of pre-existing immunity to conventional serotypes.

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