Clinical burden and outcomes of pediatric carbapenem-resistant Klebsiella pneumoniae bloodstream infections in a tertiary care center.

Sevliya Ocal Demir Seyhan Yılmaz Meryem Çağla Abacı Çapar Sıla Cura Faruk Odabaşi Ahmet Furkan Eser Ezgi Çelikboya A. Ilki Eda Kepenekli̇ G. Akkoç

Oct 2026 · European Journal of Clinical Microbiology and Infectious Diseases · 0 citations · 12 references

Medicine

TL;DR

Prior carbapenem exposure and longer antibiotic use were more frequent in the CRKP group, although the differences were not statistically significant, and white blood cell, neutrophil, lymphocyte, and platelet counts were significantly lower in patients with CRKP BSI.

DOI PubMed Semantic Scholar

View source

Similar papers

Oct 2026

Carbapenem resistance and mortality in pediatric Acinetobacter bloodstream infections: determinants from a 12-year tertiary-care cohort study

Thrombocytopenia and carbapenem resistance were associated with 30-day all-cause mortality in the primary adjusted analysis; the resistance association was not statistically significant in A. baumannii-restricted and first-episode-only sensitivity analyses.

Suleyman Emre Karauzum, Ece Erci, G. Koc et al. · European Journal of Pediatri... · 0 citations

Open access Oct 2026

Clinical factors associated with carbapenem resistance and in-hospital mortality in Klebsiella pneumoniae bloodstream infection: a 7-year retrospective cohort study

Background Carbapenem-resistant Klebsiella pneumoniae bloodstream infection (CRKP BSI) is associated with substantial mortality and limited therapeutic options, yet institutional epidemiology and risk profiles vary. We evaluated antimicrobial susceptibility, non-blood-site detection, factors associated with carbapenem...

Na Xu, Yi Liang, Wen Zhu et al. · Frontiers in Microbiology · 0 citations

Sep 2026

Clinical and Microbiologic Predictors of Progression to Infection Among Children With Enteric Colonization by Carbapenemase-producing Enterobacterales.

BACKGROUND Carbapenemase-producing Enterobacterales (CPE) colonization is rising globally, yet data on pediatric patients and the risk of progression to infection remain scarce. This study identified clinical/microbiologic profiles and risk factors for progression to infection in colonized children. METHODS This retr...

Derrick A. Fassbind, Mariana Rech, F. Motta et al. · The Pediatric Infectious Dis... · 0 citations

Open access Sep 2026

Treatment Patterns and Clinical Outcomes in Children with Stenotrophomonas maltophilia Infections

Stenotrophomonas maltophilia is an opportunistic, multidrug-resistant pathogen commonly associated with respiratory and bloodstream infections. Owing to extensive intrinsic and acquired antimicrobial resistance and limited pediatric-specific evidence, contemporary management relies heavily on extrapolation from adult d...

Carly Mitchell, T. Thomas, Angelica Rivera-Agosto et al. · Microorganisms · 0 citations

Open access Oct 2026

Real-World Use of Ceftazidime-Avibactam for Carbapenem-Resistant Enterobacterales Infections in Children: A 7-Year Cohort From a Latin American Referral Center.

BACKGROUND Pediatric data on ceftazidime-avibactam (CAZ-AVI) for carbapenem-resistant Enterobacterales (CRE) infections remain limited, particularly in Latin America, where KPC-producing organisms are endemic. We describe the clinical characteristics, microbiological profile, and outcomes of children with CRE infection...

María Gabriela Novoa Villada, A. Gouzy, Mónica Trujillo-Valencia et al. · Journal of the Pediatric Inf... · 0 citations

Open access Sep 2026

Demographic, Clinical, and Antibiotic Exposure Factors Associated with Carbapenem-Resistant Acinetobacter baumannii: An Eight-Year Retrospective Study

These findings support strengthening antimicrobial stewardship, particularly the appropriate use and continuous evaluation of carbapenem therapy, alongside enhanced surveillance and infection prevention measures among high-risk patients.

Angky Budianti, Dzaki Fadlurrahman Ayyasy, Mubarokah Mubarokah et al. · Jurnal Kesehatan dan Kedokte... · 0 citations