Sep 2026· American Journal of Psychiatry· pp.
appiajp20250793
· 0 citations
Medicine
TL;DR
LAIAs were associated with substantially less health care utilization and fewer relapses of manic and mixed episodes, and they were not associated with increased risk of nonpsychiatric hospitalizations, notably for cardiovascular disease.
The present review suggests that LAIs may represent a valuable therapeutic strategy for patients with schizophrenia and comorbid SUD, although the available evidence remains heterogeneous in terms of study design, patient populations, and outcome measures.
Matteo Lupi, A. Carano, Eros Rossi et al.· Brain Science· 0 citations
INTRODUCTION
Long-acting injectable antipsychotics (LAIs) are underused despite known benefits. This subgroup analysis from the Attitudes DriVing regional differences in LAI ANtipsychotic utilization for schizophrenia among healthcare professionals (HCPs), patients, and CaregivErs (ADVANCE) study aimed to understand fa...
K. R. Franzenburg, Rolf T. Hansen, M. Suett et al.· Psychiatry Research· 0 citations
ObjectiveDescribe concurrent use of two long-acting injectable (LAI) antipsychotics in selected patients with treatment-resistant schizophrenia and persistent aggression at a forensic health facility. Evidence remains limited for this off-licence strategy.MethodsRetrospective case series conducted at a specialist foren...
A. Rodrigo, Jacques Claassen, Daveena Mawren· Australasian Psychiatry· 0 citations
Abstract Background Literature guiding the use of long-acting injectable antipsychotics (LAIAs) versus oral antipsychotics (OAs) in people with intellectual disability (PWID) remains scarce. Objective Examining the associations of LAIAs vs OAs with healthcare utilisation among PWID. Methods This self-controlled case se...
Shek-Ming Leung, Kyung Jin Lee, Yue Wei et al.· BMJ mental health· 0 citations
A significant effect of initial dose, number of concomitant antipsychotics, and disorder duration before LAI initiation was found, and the importance of follow-up and dose reassessment after starting LAI treatment is underscored.
Tatsunori Suzuki, Keita Okinaga, Tomoe Abe et al.· Journal of Pharmaceutical He...· 0 citations
Objective: We utilized the Early Psychosis Intervention Network (EPINET) platform to examine variability in utilization rates of 2 evidence-based pharmacologic treatments, long-acting injectable (LAI) formulations of antipsychotics and clozapine.
Methods: Data come from 8 EPINET clinic consortia, called "hubs," compris...
John M. Kane, Nina R. Schooler, P. Marcy et al.· Journal of Clinical Psychiat...· 0 citations
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