ADSCs-Exo ameliorates UVB-induced skin DNA damage via p62-RNF168-dependent histone ubiquitination.

Wei Gao Chen Ai P. Song Si-Qi Li Xue-Ting Han Min-Ting Lv Fei Gao Fang-Zhou Huang Wei-Jing Chen Zhen-Zhu Li Hui-Yan Zhang Qing-Qing Li Yu-Shuai Wang

Sep 2026 · Photochemical and Photobiological Sciences · 0 citations · 54 references

Medicine

TL;DR

A novel autophagy-dependent p62-RNF168 regulatory axis governing ADSCs-Exo-mediated photoprotection is uncovered, providing a promising therapeutic strategy for ultraviolet-associated skin DNA damage and photocarcinogenesis.

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