Low-dose prasugrel versus clopidogrel for dual antiplatelet therapy after percutaneous coronary intervention: insights from the STOPDAPT-2 total cohort.
Oct 2026· Cardiovascular Intervention and Therapeutics· 0 citations· 10 references
Medicine
TL;DR
No significant differences were detected in short-term cardiovascular or bleeding outcomes between low-dose prasugrel-based and clopidogrel-based DAPT in patients after PCI without major in-hospital complications.
Among patients at high risk for ischemic events 12 months after drug-eluting stent implantation, clopidogrel monotherapy was noninferior to extended DAPT with respect to net adverse clinical events at 24 months.
Seung-Jun Lee, Yong-Joon Lee, Kyounghoon Lee et al.· New England Journal of Medic...· 0 citations
AIMS
To evaluate the 12-month clinical outcomes of short-term versus extended dual antiplatelet therapy (DAPT) in diabetic patients following drug-eluting stent (DES) implantation.
METHODS
In this single-center prospective cohort study, 536 diabetic patients undergoing DES implantation were categorized into short-ter...
R. Fan, Yu-Long Ma· Catheterization and cardiova...· 0 citations
The application of OCT for the evaluation of stent strut endothelialization provides a robust rationale for shortening DAPT duration to 1 month in patients with high hemorrhagic risk, even in the presence of concomitant diabetes mellitus and multiple comorbidities.
A. Prokhorikhin, Yu. V. Kukushkina, D. D. Zubarev et al.· Translational Medicine· 0 citations
Among patients with HR‑NICE within 24 h of onset, low‑dose ticagrelor plus aspirin significantly decreased the incidence of END within 7 days and improved neurological functional outcomes at 90 days compared with clopidogrel plus aspirin, without increasing the risk of bleeding.
Jia-Hui Liu, Hua Cao, Ming-Li Wang et al.· Journal of Neurology· 0 citations
BACKGROUND
The safety of omitting up-front treatment with aspirin during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) remains unclear.
METHODS
We conducted a multicenter, open-label, randomized trial in Japan involving patients with STEMI who wer...
Kuniaki Takahashi, Ken Kozuma, Yoshihiro Morino et al.· New England Journal of Medic...· 0 citations
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