Sep 2026· Southern medical journal (Birmingham, Ala. Print)· Vol 119 9, pp.
592-596
· 0 citations· 29 references
Medicine
TL;DR
The clinician needs to understand the risk for right-to-left shunting of PLSVC, procedural risk during placement of the catheter or device, and its association with arrhythmias and stroke, to improve procedural outcomes for patients undergoing intervention.
Abstract
Persistent left superior vena cava (PLSVC) is the most common thoracic venous anomaly, occurring in 0.3% to 0.5% of the general population and in 10% of patients with congenital heart disease. Historically considered benign, PLSVC is increasingly recognized for its clinical significance in the fields of interventional cardiology, electrophysiology, and surgery. The present narrative review combines the available evidence regarding PLSVC, focusing on its embryology, anatomical variants, diagnostic challenges, and tailored management strategies, to address clinical uncertainties and improve procedural outcomes for patients undergoing intervention. The clinician needs to understand the risk for right-to-left shunting of PLSVC, procedural risk during placement of the catheter or device, and its association with arrhythmias and stroke. Common in high-risk patients (eg, in congenital heart disorders, unexplained hypoxia), early detection by advanced imaging and forward procedural planning are key to reducing complications and optimizing patient outcomes.
Introduction: Persistent left superior vena cava (PLSVC), the most common thoracic venous anomaly, frequently coexists with congenital defects, highlighting its clinical significance. To refine risk stratification, this study compares the prenatal sonographic profile, postnatal outcome data, and genetic associations be...
Gökhan Unver, S. Serin, Huseyin Ekici et al.· Eskisehir Medical Journal Es...· 0 citations
Superior vena cava syndrome (SVCS) is a clinical condition resulting from the obstruction of venous drainage from
the head, neck, and upper limbs into the right atrium. It was first described by William Hunter in 1757. It is a diagnostic and
therapeutic emergency, particularly when signs of acute compression or life-th...
Boudiaf Rym, Zemmour Douaa, Ait Mouheb Tahar· International Journal of Inn...· 0 citations
This review covers the management of PDA in adults, highlighting the pathophysiology, morphological classification, clinical presentation, and current approaches to closure, with transcatheter closure currently the preferred approach.
Anthony J. Kaywood, Alishah Ahmadi, W. Frishman· Cardiology in Review· 0 citations
Rationale: Isolated persistent left superior vena cava (IPLSVC) is an extremely rare congenital malformation with a low overall prevalence in the general population. Most patients present without typical clinical manifestations, leading to a relatively high rate of missed diagnoses in clinical practice. Owing to abnorm...
Anatomical variations in pulmonary circulation, especially in the number and drainage patterns of pulmonary veins, have significant clinical implications. The typical anatomy includes four pulmonary veins, which transport oxygenated blood to the left atrium through distinct ostia. However, variations have been reported...
J. J. V. Branca, N. Fagni, G. Guarnieri et al.· Italian Journal of Anatomy a...· 0 citations
ABSTRACT
Coronary artery anomalies are rare but clinically significant malformations, particularly when involving an interarterial course, which predisposes to ischemia and sudden cardiac death. We report the case of a previously healthy 22-year-old man who suffered out-of-hospital cardiac arrest associated with recrea...
I. S. Coelho, Luiz F. C. Lopes, M. A. Delgado· Annals of Cardiac Anaesthesi...· 0 citations
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