Aug 2026· International Journal of Medical Informatics· Vol 220, pp.
106648
· 0 citations· 35 references
Medicine
TL;DR
LLMs hold substantial potential to enhance healthcare teamwork by supporting clinical decisions, streamlining administrative workflows, and improving patient communication, however, ethical, legal, and accountability concerns remain.
Abstract
Background
Generative artificial intelligence, particularly large language models (LLMs), has rapidly advanced and shows promise in healthcare for supporting teams through their ability to understand and generate medical text. While human-AI collaboration has been explored, the integration of LLMs into healthcare teams remains under-researched.
Objective
This scoping review aims to examine how LLMs are currently used to support teamwork and communication in healthcare teams, including both solely professional teams and those involving patients.
Methods
Following PRISMA-ScR guidelines, we registered our review with the Open Science Framework (July 30, 2025). We searched PubMed, Web of Science, and ScienceDirect for articles from 2014 to 2024. After screening 3,865 unique titles and abstracts, 127 full texts were reviewed.
Results
Twenty studies were included, predominantly employing quantitative and simulation-based designs, with limited in situ evaluations. LLM use cases were categorized into decision support, communication, and administrative functions. Outcome measures primarily focused on accuracy and quality (15/20 studies), with fewer assessing safety (4/20), readability or empathy (5/20), workflow efficiency (3/20), and error modes (2/20). Across use cases, LLMs demonstrated potential to improve efficiency and communication, although performance and risks varied by task complexity and use context.
Conclusion
LLMs hold substantial potential to enhance healthcare teamwork by supporting clinical decisions, streamlining administrative workflows, and improving patient communication. However, ethical, legal, and accountability concerns remain. Current studies largely evaluate model performance without considering the dynamics of human team members. Future research should examine LLMs' impact on trust, collaboration, and decision-making within clinical teams, while implementation efforts must address contextual and interdisciplinary factors to ensure responsible integration.
A scoping review that maps approaches for evaluation of LLM-based applications used for health purposes by nonprofessionals and will provide directional guidance for further research and development in the field of quality assurance for LLM-based applications used by nonprofessionals is outlined.
Maren Keuchel, Pinar Bisgin, Tom Strube et al.· JMIR Research Protocols· 0 citations
Multilingual AI chatbots demonstrate a boost in healthcare efficiency, a reduction in language barriers, and the promotion of health equity, but exhibit challenges regarding validation, workflow integration, and evaluation standards, along with ethical issues such as privacy and bias.
R. Sharanesha, Deepti Virupakshappa, A. Abushanan et al.· Informatics· 0 citations
It is suggested that the reliability of health care LLM reliability is difficult to evaluate adequately using a single universal standard, and future evaluations of health care LLM reliability need to be guided by standardized evaluation frameworks that reflect domain-specific contexts.
Euijun Yang, S. Ko, Hyekyung Woo· Journal of Medical Internet...· 0 citations
A pragmatic adoption approach is emphasized to prioritize high-volume, lower-risk clerical and communication workflows; maintain clinician verification and accountability; and apply governance and equity safeguards before scale-up before scale-up.
Michael Christof, Krish Patel, Jian-Dong Zhou et al.· Communications Medicine· 0 citations
Current evidence suggests that LLMs have considerable potential to support future ICU handoff workflows but substantial evidence gaps remain and prospective evaluation in real-world ICU settings, with clinically meaningful safety metrics and structured communication frameworks, is needed.
S. Bains, Michael R Kolesnikov, S. Bedrick et al.· Considerations in Medicine· 0 citations
The scoping review highlights that large language models can only serve as assistive tools in the development of nursing care plans, while nurses remain the primary decision-makers, and underscores the need to enhance nurses' AI literacy to strengthen human-AI collaboration.
Jian-Wen Zeng, Xu-Le Zhu, Shi-Ying Shen et al.· Journal of Clinical Nursing· 0 citations
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