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Single-cell and spatial transcriptomics identify a JUNB+ neutrophil subset enriched in immune-excluded regions of lung adenocarcinoma

Ya-Ping Zhu Dan-Fei Shi Long-Fei Ji Bin-Yu Wang Wei-Yun Shen Feng-Qi Liu Si-Qi Zhang Xin-Min Li Yong Li
Oct 2026 · Inflammation Research · Vol 75 · 0 citations · 48 references
Medicine

TL;DR

The neutrophil-specific upregulation of JUNB highlights its potential as a circulating biomarker for TAN-mediated immunosuppression, which warrants validation in prospective cohorts.

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