Sep 2026· Sisli Etfal Hastanesi tip bulteni· Vol 60, pp. 417 - 420· 0 citations· 12 references
Medicine
TL;DR
The case of a 26-year-old woman who presented with abdominal pain, weight loss, and fatigue and underwent radical nephrectomy followed by adjuvant chemotherapy, including doxorubicin, vincristine, and actinomycin D is presented.
Abstract
Wilms tumor (WT) is the most common renal malignancy in children but can be challenging to diagnose in adults because its clinical and imaging features often mimic those of renal cell carcinoma (RCC). Most diagnoses are made incidentally following nephrectomy performed for suspected RCC. Due to the lack of established adult-specific treatment guidelines, management typically follows pediatric protocols. This report presents the case of a 26-year-old woman who presented with abdominal pain, weight loss, and fatigue. Imaging revealed a large, irregular mass in the left kidney, which was confirmed as WT after nephrectomy. She underwent radical nephrectomy followed by adjuvant chemotherapy, including doxorubicin, vincristine, and actinomycin D. After two years of follow-up, recurrence was detected, leading to a second surgery followed by radiotherapy. This case highlights the diagnostic and therapeutic challenges associated with adult WT and emphasizes the need for individualized treatment strategies tailored to each patient.
Introduction Nephroblastoma is the most common malignant renal neoplasm in children but remains exceptionally rare in adults. Compared with pediatric cases, adult Wilms tumor (AWT) often presents greater diagnostic challenges and is associated with larger tumor volumes and more advanced disease at diagnosis, contributi...
Kun Wang, Jin Long, Cheng Pan et al.· Frontiers in Surgery· 0 citations
Nephroblastoma, also known as Wilms tumor, is the most common type of kidney cancer found in pediatric patients. The majority of cases (75%) occur in children aged 1–5 years, with a peak incidence at approximately 3 years of age. Hematogenous spread primarily involves the lungs (81%), followed by the liver and lungs (1...
Ying Bi, Hai-Yang Jiang, Shang-Hu Qu et al.· Journal of International Med...· 0 citations
Renal cell carcinoma is the most common adult renal malignancy but is rare in children, where Wilms tumor predominates. A 10-year-old boy presented with intermittent gross hematuria for two years, worsening with clot retention. Imaging revealed a right renal solid mass without metastasis (cT1bN0M0). After cystoscopic c...
Agung Damai Harikatang, Safendra Siregar, Ghani Ikhsan Majid· Urology Case Reports· 0 citations
Renal glomus tumor (GT) is a rare neoplasm originating from glomus cells within the kidney. The subtype designated as uncertain malignant potential (UMP) is particularly rare, with limited literature available. Its clinical presentation and imaging features closely resemble those of renal cell carcinoma (RCC), making a...
Tong-Zhen Yan, Xue-Hao Zhou, Li-Qiang Guo· Journal of Kidney Cancer and...· 0 citations
Wilms tumor is the most common pediatric renal neoplasm. The diagnosis of Wilms tumor is made on imaging when the radiological features and age of presentation are typical. Percutaneous biopsy is reserved for cases with atypical imaging appearance or older age at presentation, as the biopsy itself upgrades Wilms tumor...
S. L. Mohan, Stuti Chandola, Sandeep Agarwala et al.· Current problems in diagnost...· 0 citations
ABSTRACT
Primary neuroendocrine tumors (NETs) of the kidney are exceedingly rare, with an estimated incidence of only 0.13 per 1 million individuals. Their rarity is attributed to the absence of native neuroendocrine cells within the renal parenchyma. These tumors span the WHO grading spectrum, with well-differentiated...
Sandeep Kaur, Vandana Rana, Neeti Goyal et al.· Indian Journal of Pathology...· 0 citations
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