Aug 2026· Journal of Imaging· Vol 12· 0 citations· 47 references
Medicine
TL;DR
Results indicate the WVM-UNet architecture effectively captures discriminative features for precise medical image segmentation, and demonstrates the competitive performance of the method on multiple public datasets.
Abstract
Accurate segmentation of skin lesions and gastrointestinal polyps is essential for early diagnosis and treatment planning. Currently, Convolutional Neural Networks (CNNs) are limited by local receptive fields, missing small lesions. While Transformers model global context, their quadratic computational complexity incurs high costs. To address these limitations, we propose the Wavelet–Vision Mamba UNet (WVM-UNet), integrating State Space Models (SSMs) for linear-complexity long-range dependencies and wavelet transforms for fine-grained feature extraction. The network employs a Wavelet-based Residual State Space (WRSS) block, combining the multi-scale decomposition of discrete wavelet transforms with Vision Mamba to efficiently capture global features. A Fused Channel–Spatial Attention (FCSA) mechanism is incorporated to adaptively recalibrate feature representations. Additionally, we construct an Encoder–Decoder Semantic Connection (EDSC) to replace traditional skip connections, effectively bridging the semantic gap between cross-level features. Experimental results on multiple public datasets demonstrate the competitive performance of our method. Specifically, on the ISIC 2017 dataset, WVM-UNet achieves an mIoU of 82.94% and a DSC of 90.67%, outperforming the Mamba-based VM-UNet by 2.71% in mIoU. These results indicate our architecture effectively captures discriminative features for precise medical image segmentation.
Medical image segmentation is a critical task in computer-assisted diagnosis, but accurate delineation remains challenging in sensor-captured dermoscopic and endoscopic images because of low contrast, blurred boundaries, acquisition artifacts, and large appearance variations. Although CNN-based methods are effective in capturing local texture and boundary cues, they often struggle to explicitly model long-range dependencies and global structural relationships. Transformer-based architectures can capture global context, but their self-attention mechanism may become computationally costly when processing high-resolution feature maps. To address these challenges, we propose MGA-UNet, a frequency-aware multi-scale encoder–decoder segmentation framework that integrates wavelet-based frequency decomposition with Mamba-based long-range dependency modelling. Specifically, the Wavelet-Mamba feature extraction backbone (WMB) decomposes features into low- and high-frequency components to enhance boundary-aware representation, the Gated Multi-scale Aggregation Module (GMAM) aggregates parallel multi-scale encoder features and applies a content-dependent gate to the fused response, and the Adaptive Sparse Attention Module (ASAM) refines bottleneck representations with sparse attention for global semantic modelling. Across three independent runs with random seeds 42, 123, and 2026, MGA-UNet achieves mean Dice Similarity Coefficients of 88.92±0.04%, 88.01±0.07%, and 85.91±0.04% on ISIC2018, ISIC2017, and Kvasir-SEG, respectively. These results demonstrate competitive segmentation performance among the compared representative CNN-based, Transformer-based, and Mamba-based methods, including the recent H-VMUNet baseline. These results indicate that frequency-domain decomposition and state-space modelling can complement each other for accurate medical image segmentation, particularly in images with ambiguous boundaries and complex background interference.
Shuai-Kang Qiu, Xuan Wang, Kaile Su et al.· Italian National Conference...· 0 citations
A Pixel–Region VSSblock that comprises a local-Mamba branch and a global-Mamba branch to simultaneously capture fine-grained details and high-level semantic context and a Hierarchical Feature Calibration Module (HFCM) that leverages multi-scale context awareness and a structural saliency filtering mechanism to dynamically calibrate the skip connections, effectively suppressing feature redundancy while enhancing semantic interaction quality.
Medical image segmentation requires high accuracy and robustness, yet practical commercial deployment also demands privacy preservation and computational efficiency. In this context, the U-Net architecture, which can be inherently decoupled into independent encoder and decoder components, serves as a natural commercial choice. However, pure Transformer-based variants like Swin-UNet often suffer from insufficient local detail capture and limited interpretability. In this paper, we propose a lightweight hybrid architecture built upon the Swin-UNet framework. Our model integrates a parallel CNN encoder to complement the shallow layer reasoning of Swin Transformers with local texture features. To bridge the semantic gap and enhance fine-grained spatial detail recovery, we design an asymmetric feature fusion strategy and introduce cross-layer skip (XSkip) connections that explicitly propagate shallow CNN features into the decoder. We further incorporate novel loss functions and an auxiliary supervision head (Aux-Head) to strengthen training stability, boundary delineation, and intermediate feature interpretability. Extensive experiments on the Synapse multi-organ segmentation dataset demonstrate that our approach achieves state-of-the-art competitive Dice scores and Hausdorff distances, offering an accurate, efficient, and interpretable solution for clinical deployment.
Segmentation of medical images is a crucial process for diagnosis and treatment planning. Yet, traditional CNN based models are often not able to convey high-level spatial relationships and intricate tissue boundaries in high-resolution medical images. To tackle these issues, this paper presents a novel ResUNet++–Vision Transformer (ResUNet++–ViT) framework incorporating both multi-scale local feature extraction and global contextual learning. The ResUNet++ backbone consists of residual blocks and nested skip connections, which are used to extract hierarchical features, and the Vision Transformer uses self-attention mechanisms to capture long-range dependencies. A fusion module allows for the integration of local and global features, resulting in better segmentation accuracy and preserving the boundary. The proposed model was tested on the ISBI 2012 Electron Microscopy Segmentation Challenge (EMSC) dataset, and obtained a Dice score of 0.960, IoU of 0.920, precision of 0.967, recall of 0.958, accuracy of 0.984 and Hausdorff distance of 2.76. The proposed framework is compared with FCN, UNet, Attention UNet, ResUNet, UNet++, Vision Transformer and TransUNet, and the results show its superiority. The results show that the combination of ResUNet++ and Vision Transformers greatly enhances the performance of segmentation, boundary delineation, and generalization in the field of advanced medical image analysis applications.
G. Satyanarayana, Kadali Satyanarayana, Renuka Kondabala et al.· 2026 International Conferenc...· 0 citations
Accurate polyp segmentation is critical for computer-aided colonoscopy, yet endoscopic images often contain low-contrast boundaries, mucosal texture interference, specular highlights, and device-dependent appearance shifts. Vision State Space Models (SSMs) provide efficient long-range modeling with linear complexity, but existing Vision Mamba segmentation models typically convert 2D features into 1D scanning sequences, which may weaken local geometric continuity and over-smooth irregular contours. We propose CSG-Mamba, a convolutional scoring gating Vision State Space network for endoscopic polyp segmentation. Built on a VM-UNet-style asymmetric U-shaped encoder-decoder, CSG-Mamba inserts a Convolutional Scoring Gating (CSG) module at the semantically rich bottleneck. CSG generates a local spatial score map through pointwise and large-kernel depthwise convolutions and recalibrates state-space features by multiplicative gating. Experiments with three random seeds show that CSG-Mamba achieves 0.9220 Dice and 15.87 HD95 on Kvasir-SEG, and 0.7418 Dice and 0.6570 mIoU on CVC-ColonDB, outperforming the baselines on most overlap and recall metrics while maintaining competitive boundary accuracy.
Yuliang Wang, Jiaqi Wu, Jiaye Song et al.· 0 citations
Medical imaging plays an essential role in the early detection and clinical assessment of multiple diseases; however, manual image interpretation is time-consuming and can be affected by inter-observer variability, particularly when subtle pathological patterns are present. Conventional convolutional neural networks (CNNs) provide strong local feature extraction but may inadequately capture long-range spatial dependencies, whereas Vision Transformer-based architectures effectively model global contextual relationships but can require substantial training data. To exploit their complementary capabilities, this study proposes a Hybrid CNN-Transformer Framework for Multi-Disease Detection from Medical Imaging Data. The proposed architecture employs a multi-scale CNN backbone to extract local texture, boundary, morphological, and lesion-level characteristics, followed by Transformer-based self-attention to capture long-range dependencies among spatial feature representations. An attention-guided feature-fusion module integrates local CNN features with global Transformer representations, and the resulting discriminative embedding is processed by a multi-class classification layer for disease prediction. Data augmentation, class-aware training, and regularization are incorporated to improve robustness under heterogeneous medical-image distributions. Under the proposed experimental configuration, the hybrid framework achieves an overall accuracy of 96.74%, sensitivity of 95.92%, specificity of 97.18%, precision of 96.31%, F1-score of 96.11%, and area under the receiver operating characteristic curve (AUC) of 0.986. Compared with the selected standalone CNN baseline, the proposed approach provides approximately 5.2% relative improvement in accuracy and 5.8% improvement in F1-score. The combined local-global representation also improves discrimination of visually similar disease categories compared with individual CNN and Transformer models. These findings demonstrate the potential of hybrid CNN-Transformer architectures for robust and scalable computer-assisted multi-disease screening from medical imaging data. The proposed framework is intended to support clinical image assessment and prioritization rather than replace expert diagnosis.
M. Balakrishnan, K. Ananthi, S. R. et al.· International journal of com...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
