Across cumulative ablations and ultra-rare-disease benchmarks, a PIHF-derived policy improved Recall@1 in one proprietary executor and three open-weight executors spanning 3 to 49 billion active parameters.
Abstract
Generative pretraining established reusable task representations; later work on language-based task conditioning and in-context learning showed that a fixed model could adapt its behavior from instructions and demonstrations. Policy Iteration with Human Feedback (PIHF) builds on this development and the recurrent evaluate-and-improve structure of generalized policy iteration. PIHF uses a pretrained language model as its execution substrate and moves persistent revision to a versioned natural-language policy and tool set. A language-model critic and clinical expert review complete-panel reasoning and tool-use trajectories to localize recurrent failures and form candidate revisions; the expert may reinterpret the evidence and retains authority over admission and rollback, while Recall@1 and Recall@5 validate outcomes after candidate execution. Across cumulative ablations and ultra-rare-disease benchmarks, a PIHF-derived policy improved Recall@1 in one proprietary executor and three open-weight executors spanning 3 to 49 billion active parameters. Gains were 32.7 percentage points for GPT-5.4 and 31.1 points for Qwen3.6-35B, a difference of 1.7 points. These results support the feasibility of using pretrained language models as fixed-weight execution substrates for expert-guided policy development in rare-disease diagnosis.
SEED (SElf-Evolving On-Policy Distillation), a self-evolving framework that converts completed on-policy trajectories into training-time hindsight skills and distills their behavioral effect back into the policy model, is proposed.
Jinyang Wu, Shuo Yang, Zhengxi Lu et al.· arXiv.org· 7 citations
Desc descriptive evidence is provided that long-horizon multi-tool post-training can change ways of working that transfer beyond its training domain, and both software-engineering benchmarks improve despite the training collection containing no software-engineering tasks.
Sushant Mehta, Logan Ritchie, Liudas Panavas et al.· 0 citations
Self-Review Reinforcement Learning consistently outperforms the RLVR in final reward performance and achieves greater learning efficiency by successfully transforming feedback into behavioral improvement.
Conditional experience transfer is formulated as conditional experience transfer and Boundary-Calibrated Intervention Transfer is introduced, a method that authorizes experience reuse before weight-changing training and attains higher equal-budget final-model quality than the evaluated alternatives.
Ting Li, Wenfeng Feng, Weiqing Li et al.· 0 citations
Production large language model (LLM) based systems such as coding agents, web navigators, and tool-calling assistants operate over multiple turns of interaction with users, tools, and environments. Pretrained LLMs, depending on their size, can either underperform in these settings due to misalignment with the system's interaction mechanics, or, when capable, incur prohibitive latency. Fine-tuning right-sized models addresses both accuracy and latency, but training such multi-turn agents requires Reinforcement Learning (RL), where the model acts as a policy optimizing long-horizon outcomes across sequential interactions. This poses challenges absent from single-turn settings: credit assignment over long trajectories, reward design for sparse and delayed feedback, state and context management as observation histories grow, environment scaling for parallel rollout collection, and training stability under prompt/environment distribution shift. This hands-on problem-solving tutorial provides both a rigorous algorithmic and practical introduction to multi-turn RL finetuning for LLMs. Using Amazon SageMaker AI, participants progress through four labs: (1) environment and reward function design, (2) multi-turn trajectory collection and Group Relative Policy Optimization (GRPO)-based training, (3) reward densification and credit assignment strategies, and (4) evaluation, failure diagnosis and deployment. We cover state-of-the-art multi-turn RL finetuning algorithms, turn-level vs. trajectory-level reward design, and production grade monitoring for reward hacking detection. The tutorial targets machine learning (ML) engineers, data scientists, and researchers who build agentic LLM systems. No prior RL experience is required. All materials will be publicly available on GitHub.
Zhe Wang, Sapana Chaudhary, Jiayu Li et al.· Proceedings of the 32nd ACM...· 0 citations
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