Chagas disease: the peculiar relationship between parasite and host.

Post-Dengue Syndrome: From Immunopathogenesis to Multisystemic Clinical Sequelae

This narrative review analyzes the cytokine storm, antibody-dependent enhancement, and NS1-triggered molecular mimicry of dengue virus, offering an immunoclinical perspective for the multidisciplinary management of these patients.

Canine babesiosis: From classical concepts to new insights

Canine babesiosis is one of the most important vector-borne protozoal diseases of dogs. However, the past two decades have brought significant advances in our understanding of the biology, epidemiology, and pathogenesis of this long-recognized parasite. The development of molecular diagnostic methods has enabled the re...

Visceral leishmaniasis: an integrated review of resistance mechanisms, host immunometabolism, and next generation therapeutics

Phosphatidylserine Blockade Limits Systemic Dissemination of Leishmania Amazonensis Amastigotes

Leishmania amazonensis is associated with cases of cutaneous, disseminated, diffuse, mucosal, and visceral leishmaniasis (VL). The mechanisms underlying its ability to persist and spread after the initial clinical cure are unclear, although intrinsic characteristics of the parasite and the host may be involved. Phospha...

In vitro investigation of the host-pathogen interaction in human strongyloidiasis at the intestinal level

Human strongyloidiasis is a chronic long-lasting infection caused by the helminth parasite Strongyloides stercoralis , characterised by a peculiar autoinfective cycle. The interplay between the parasite and the host should hence entail mechanisms of adaptation to tolerate the chronic presence of this nematode....

FEATURES OF THE INFECTIOUS PROCESS OF AFRICAN SWINE FEVER

The article presents a comprehensive analysis of the pathogenesis features of African swine fever (ASF) – a highly dangerous viral contagious disease affecting wild and domestic pigs of all breeds and ages. The main stages of pathogenesis are considered: portals of entry of infection, primary and secondary viremia, vir...