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AJP authors propose broader definition of resistant schizophrenia

Aug 2026 · Mental Health Weekly · Vol 36 · 0 citations

Abstract

A proposal to expand the definition of treatment‐resistant schizophrenia (TRS) could help clinicians identify patients earlier and improve access to effective interventions, according to authors of new commentary published in the American Journal of Psychiatry (AJP). The authors argue that current definitions may not fully capture the range of patients whose symptoms fail to respond adequately to antipsychotic treatment.

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