This review critically evaluates the role of diet–microbiota interactions in CVD pathogenesis and provides an integrated, metabolite-centered perspective on how major dietary patterns influence gut microbial metabolism and cardiovascular health.
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality globally. Increasing evidence identifies the gut microbiota as one of the major regulators of cardiovascular health, leading to the concept of the gut–heart axis. Metabolites from microbiota serve as key mediators linking intestinal micr...
M. E. Ceyhan, Gentiana Mehmeti, S. N. Cukurova et al.· International Journal of Mol...· 0 citations
Cardiovascular disease (CVD) continues to rank among the primary drivers of human mortality, creating an urgent requirement for multifaceted prevention and clinical intervention plans. Apart from conventional medications, surgical operations, and, interventional therapies, therapeutic strategies centered on gut microbi...
The gut microbiota plays a significant role in cardiovascular disease (CVD), through its metabolic products. Tryptophan is a key signaling molecule in the microbiota–host network; its gut microbial metabolites, including indole derivatives, kynurenine and serotonin, have dual effects on cardiovascular homeostasis. This...
Qian Ding, Si-Qi Li, Mu Guo et al.· Frontiers in Microbiology· 0 citations
Alterations in gut microbial ecology have been linked to obesity, type 2 diabetes (T2D), and hypertension, but their biological significance remains difficult to separate from diet, medication use, adiposity, and other host factors. We synthesize evidence on intestinal barrier dysfunction, microbial translocation, low-...
Jhommara Bautista, Ronald Hernández-León, Alexandra S. Valencia-Valverde et al.· Frontiers in Endocrinology· 1 citation
This review critically summarizes evidence linking the Mediterranean diet, gut microbiome, microbial metabolites, and cardiovascular disease risk, with emphasis on the shift from microbial taxonomy to functional pathways, multiomic integration, and translation to precision nutrition. Mediterranean diet adherence is ass...
Adrián Hernández-Cacho, Jia-Qi Ni, J. García-Gavilán et al.· Current Atherosclerosis Repo...· 0 citations
Obesity and type 2 diabetes mellitus (T2DM) are major metabolic disorders shaped by interactions among diet, host physiology, and the gut microbiota. Growing human evidence indicates that dietary fiber, prebiotics, probiotics, synbiotics, polyphenols, fermented foods, and Mediterranean-style dietary patterns can alter...
Bibi Mariam· Natural Resources for Human...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
