Clinical management strategies for HPV associated warts are studied, including primary destructive treatment, immunotherapies, and novel adjunctive therapies with clinical evidence including photodynamic therapy, intralesional chemotherapeutics, and emerging HPV vaccination strategies.
In conclusion, incorporating genomics, transcriptomics, immunotherapy, and artificial intelligence will enable more personalized and effective interventions, ultimately reducing the global burden of cervical cancer.
Yu-Bing Zhou, Yun-Xiao Ge, Kang-Dong Liu et al.· Cellular and Molecular Life...· 0 citations
Human papillomaviruses of the beta genus (beta-HPV) are ubiquitous components of the cutaneous virome, persistently colonizing the skin of immunocompetent individuals from early infancy. Unlike their alpha counterparts, which drive mucosal carcinogenesis through viral integration and sustained oncoprotein expression, b...
Sayma Vizcarra-Ramos, Jesús García-Gómez, W. Rojo-Contreras et al.· Pathogens· 0 citations
Background: Human papillomavirus (HPV) infection is the primary etiology of cervical cancer and its immediate precursors, collectively known as cervical intraepithelial neoplasia (CIN). Although primary prevention via prophylactic vaccination and secondary screening have significantly reduced incidence, cervical cancer...
Wiktor Śliwiński, Jakub Mazur, M. Kosowski et al.· International Journal of Inn...· 0 citations
Clinical evidence regarding NF-κB activation in persistent cervical high-risk HPV infection is synthesized and mechanistic insights from molecular studies are integrated to develop a translational framework for therapeutic intervention.
Maryam Mashhadi Abolghasem Shirazi· International Reviews of Imm...· 0 citations
Human papillomavirus (HPV) is the principal etiological factor in the majority of cervical, oropharyngeal, anal, and vulvar cancers. Persistent infection with high-risk HPV types promotes immune evasion, malignant transformation, and tumor progression. Currently licensed prophylactic HPV vaccines, based on L1 virus-lik...
A. Alsalloum, Alena P. Zakhareva, J. Lopatnikova et al.· Frontiers in Immunology· 0 citations
Human papillomavirus (HPV) is a major factor in the etiology of cervical intraepithelial neoplasia (CIN) and cervical cancer, which ranks fourth worldwide in prevalence among cancers in women. The pathogenesis of HPV-associated lesions is based on the expression of E6 and E7 oncoproteins, which disrupt cell differentia...
Aida Gilyadova, Solomon O. Onozha Solomon O. Onozha, Elizaveta Kulikova et al.· Voprosy ginekologii akušerst...· 0 citations
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