Concurrent radiosensitising regimens for bladder-preserving radiotherapy in non-metastatic muscle-invasive bladder cancer: a systematic review and structured evidence synthesis with exploratory network meta-analysis.
The optimal timing and fractionation of perioperative stereotactic radiotherapy for resected brain metastases remain uncertain. We evaluated the comparative evidence for preoperative and postoperative stereotactic treatment and the validity of indirect comparisons.
We searched PubMed/MEDLINE, CENTRAL, Web of...
Tian-Si Zhao, Shan Lu· Frontiers in Oncology· 0 citations
Prolonged overall treatment time (OTT) during definitive radiotherapy has long been considered detrimental in cervical cancer, but the magnitude and consistency of its prognostic association across treatment eras remain uncertain. We evaluated the association between OTT and oncologic outcomes after definitive radi...
Ying-Ding Ruan, Yun Li, Dan Wu et al.· Frontiers in Oncology· 0 citations
Background: Definitive concurrent chemoradiotherapy (CRT) is a standard-of-care treatment for multiple locally advanced solid malignancies, including head and neck, cervical, esophageal, and non-small cell lung cancers. While randomized controlled trials (RCTs) consistently demonstrate improved survival with CRT compar...
Jamal Uddin, Harun Or Roshid, Sujan Mahamud et al.· International Journal of Dru...· 0 citations
Moderate hypofractionation achieved disease control similar to conventional fractionation with acceptable toxicity, including in patients receiving elective pelvic lymph node irradiation, and support extension of moderate hypofractionation to patients requiring pelvic treatment and the need for prospective validation a...
C. Raynaud, Diane Jornet, S. Guillerm et al.· Cancer Radiothérapie· 0 citations
It is suggested that SBRT provides effective local control and meaningful symptom relief for spinal metastases from prostate cancer, with acceptable toxicity, and the role of SBRT in modifying disease progression and survival, particularly in CRPC.
Aaditya Dravid, Suvan Sundaresh, David Wang et al.· Neurosurgical review· 0 citations
BACKGROUND
Pancreatic ductal adenocarcinoma (PDAC) has poor outcomes and high rates of locoregional recurrence. MASTERPLAN evaluated whether stereotactic body radiotherapy (SBRT) reduced locoregional recurrence in patients with high-risk, localised PDAC.
METHODS
MASTERPLAN was an open-label, randomised, phase 2 trial...
A. Oar, A. Kneebone, K. Sjoquist et al.· The Lancet Oncology· 0 citations
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