TL;DR
This narrative review systematically evaluates the intellectual trajectory of the micro/nanoplastics/NPs domain, emphasizing how the rapid desorption of drug payloads in simulated human gastrointestinal environments transforms ambient pollution into a hypothesized public health concern.
The extensive buildup of plastic waste has become a significant environmental issue, especially due to the conversion of microplastics (MPs) into nanoplastics (NPs). In this review, we address the critical processes that lead to the fragmentation of MPs into NPs, including physical, chemical, and biological degradation...
Plastics are an integral part of modern society; however, their environmental persistence has led to widespread contamination, posing significant ecological and human health risks. Microplastics (MPs) and nanoplastics (NPs) raise concerns because of their small size and ability to penetrate biological systems, leading...
Micro- and nanoplastics (MNPs) have emerged as widespread environmental contaminants with growing implications for human health. Growing evidence indicates that the gastrointestinal tract is not only the primary site of exposure but also a central regulator of systemic toxicity through interactions among the intestinal...
A hypothesis-generating mechanistic framework in which MPs/NPs may influence cancer-related processes through the integration of environmental exposure, epithelial barrier disruption, immune dysregulation, and tumor microenvironment remodeling is proposed.
Microplastics (MPs) have emerged as pervasive pollutant, now detected across the globe, including in remote and isolated ecosystems. With rising MP contamination, concerns over their impacts on living systems have intensified. While numerous studies report adverse effects of MPs, comprehensive analytical insights into...
Current evidence regarding environmental exposure pathways, biodistribution, and molecular mechanisms of MNP-induced toxicity are integrated, emphasizing the need for integrated exposome-based approaches, omics technologies, advanced experimental models, and longitudinal studies to improve human health risk assessment...
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