Immunoinformatics-guided design of a conserved multi-epitope vaccine candidate against pathogenic human coronaviruses.

Proteome conserved multi-epitope-based vaccine construct against Nipah virus.

Structure-Guided Immunoinformatics for the Rational Design of a Multi-Epitope Vaccine Against Batai Orthobunyavirus

This study presents a structurally optimized and validated multiepitope vaccine candidate against the emerging Batai orthobunyavirus, identifying a promising vaccine candidate for further investigation; however, its immunogenicity, safety, and protective efficacy before further vaccine development can be considered.

Immunoinformatics-Based Multi-Epitope Vaccine Design Against Influenza A (H1N1) Hemagglutinin

The designed HA-based multi-epitope vaccine demonstrated promising immunogenicity, safety, structural stability, and broad population coverage in silico, and its potential as a vaccine candidate against Influenza A (H1N1) is supported.

Immunoinformatics-based design and in silico evaluation of a PstS-derived multi-epitope vaccine candidate against Salmonella typhimurium

The proposed multi-epitope vaccine shows promising immunological and structural properties, supporting its potential against S. typhimurium, pending experimental validation.

Harnessing reverse vaccinology for the design and validation of mRNA vaccine targeting the glycoprotein of human metapneumovirus (HMPV)

The two proposed multi-epitope mRNA vaccine constructs showed promising immunogenic, safety, and structural properties in silico, highlighting their potential as candidate vaccines against HMPV.

Immunoinformatics-guided in silico design of a multi-epitope peptide vaccine against Mycobacterium tuberculosis

A computationally validated multi-epitope peptide vaccine construct with strong immunogenicity were generated, but validation through the in-vitro and in-vivo study of the developed vaccine is essential to assess its efficacy and immunogenicity profile.