Long Non-Coding RNA PART1 in Alzheimer’s Disease: Clinical Value and Improvement of Neurotoxicity and Apoptosis via miR-770-5p

LncRNA FBXL19-AS1 regulates the miR-650/ITGB3 axis to drive pathological progression in Alzheimer’s Disease

FBXL19-AS1 appears to interact with and modulate miR-650, thereby affecting ITGB3 expression and potentially participating in the pathological progression of AD.

miR-584-5p suppresses Aβ1-42-induced apoptosis in Alzheimer's disease cell model via targeting of HDAC1.

LncRNA Loc646329 modulates Alzheimer’s disease-related phenotypes through the miR-150/WNT/β-catenin axis in cellular and APP/PS1 mouse models

Findings provide preclinical evidence that the Loc646329/miR-150/WNT signaling axis contributes to neuronal survival and modulates AD-related pathological changes.

The SNHG16/miR-485-5p axis exacerbates neuronal injury in pediatric temporal lobe epilepsy.

SNHG16 is highly expressed in pediatric TLE and has certain diagnostic potential and exacerbates epilepsy-related neuronal damage by binding to and suppressing miR-485-5p function, which provides novel insights into understanding the disease mechanism.

LncRNA NR2F1-AS1 serves as a diagnostic biomarker for diabetic peripheral neuropathy and promotes disease progression by regulating miR-150-5p.

BACKGROUND Diabetic peripheral neuropathy (DPN) is a common intractable complication of type 2 diabetes mellitus (T2DM), lacking specific diagnostic markers and therapeutic targets. OBJECTIVES This study explored the clinical value of NR2F1-AS1 in DPN and clarified its molecular regulatory mechanism in DPN progressio...

Circ_0004801 promotes tau hyperphosphorylation and cognitive impairment in Alzheimer's disease through the miR-7688-5p/TTBK1 axis.

Circ_0004801 acts as an upstream regulator of TTBK1 by sequestering miR-7688-5p, thereby promoting tau hyperphosphorylation and cognitive impairment in AD and may represent a potential target for tau-directed intervention.