Summary How does the human brain represent how far apart in time two remembered moments occurred? Healthy adults played a first-person interactive video game and subsequently judged the temporal order of pairs of event moments during functional MRI. Using representational similarity analysis, we identified a distributed multivoxel activity pattern in the precuneus and surrounding posterior medial cortex whose representational geometry tracked retrieved temporal-distance magnitude across intervals ranging from less than 1 s to approximately 18 min. This representation could not be explained by perceptual similarity, situational change, or task difficulty, and was stronger for events sharing a common episodic context. Applying inhibitory brain stimulation to the precuneus before retrieval attenuated this representational pattern while leaving overall BOLD activity levels unchanged. These findings suggest that the precuneus contributes to organizing temporal relationships among remembered events, representing temporal distance within structured episodic contexts rather than as a simple metric of elapsed time.
Pursuing longer-term goals relies on representations of task context that can be maintained over long periods of time and switched flexibly when goals change. Little is known about the neural substrate for maintaining context representations on the minute-timescale on which human behaviour frequently persists. Utilizin...
Hristos S. Courellis, Michael Kyzar, Juri Minxha et al.· Nature Human Behaviour· 0 citations
This work investigated whether naturalistically encoded memories that were either episodic or additionally embedded in a navigational experience relied on overlapping or distinct neural networks in the hippocampus, ERC, and lateral occipital cortex.
Kim V. Nguyen, L. Skalaban, Büşra Tanrıverdi et al.· Journal of Cognitive Neurosc...· 0 citations
Remembering temporally-extended experiences requires integrating information over time into coherent event representations that can be stored and later retrieved. Oscillatory dynamics may provide a flexible mechanism to support these operations by coordinating communication across regions and organizing neural activity...
Marta Silva, Xiong-Bo Wu, Marc Sabio et al.· bioRxiv· 0 citations
Humans must store and retrieve distinct implicit motor memories in different contexts. Recent research has revealed the motor adaptation system’s sensitivity to contextual cues related to posture, spatial goals, and visual inputs. However, to date, the role of one critical variable in implicit motor memory retrieval –...
Apoorva Sharma, Hanna Hillman, S. McDougle· bioRxiv· 0 citations
The neural mechanisms underlying the brain's representation of event gist remain poorly understood. In this study, we investigate the neural architecture and computational principles governing the hierarchical representation of event gist in the human brain. Using an integrative approach that combines natural language...
Kai-Zhou Li, Peng Ren, Qiu-Yi Liu et al.· NeuroImage· 0 citations
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