2025· International Journal of Modern Innovations and Emerging Trends· 0 citations
TL;DR
A thorough review of the developments in LLM technologies, their uses in clinical and administrative settings, as well as their ethical considerations are reviewed to suggest a conceptual structure for responsible implementation that will ensure both technological innovation and patient safety, as well as regulatory compliance and ethical health care practices.
Abstract
The Large Language Models (LLMs) are one of the most impactful technologies in artificial intelligence, showcasing astonishing natural language understanding, medical knowledge representation, clinical decision support and healthcare communication. The incorporation of LLMs into healthcare systems can have a profound impact on enhancing diagnostic precision, patient engagement, clinical documentation, medical research, and tailored treatment planning. LLMs can be utilized to analyze vast biomedical datasets, extract key information, aid clinical decision-making, and summarize complex medical records, due to their ability to process large amounts of information and understand complex patterns using advanced deep learning architectures. However, the use of LLMs in healthcare brings significant ethical, legal, technical and regulatory issues. Many challenges still stand in the way of large-scale implementation, such as patient privacy concerns, data security, algorithmic bias, explainability, misinformation, accountability, transparency, and regulatory compliance. In addition, there is a need for careful evaluation and ongoing monitoring of the performance of the models to guarantee fairness and reliability for different patient groups. The present paper is a thorough review of the opportunities and ethical concerns related to LLM in healthcare. It reviews the developments in LLM technologies, their uses in clinical and administrative settings, as well as their ethical considerations. In addition, the paper suggests a conceptual structure for responsible implementation that will ensure both technological innovation and patient safety, as well as regulatory compliance and ethical health care practices. The results offer insights that can guide and inform researchers, healthcare practitioners, policy makers, and AI developers in the design and development of trustworthy, transparent, and human-centered intelligent healthcare systems.
The integration of Large Language Models (LLMs) into healthcare is poised to revolutionize various aspects of medical practice, including clinical decision‐making, patient care, and medical research. This review explores the applications of LLMs such as ChatGPT‐3, ChatGPT‐4, and BERT in healthcare, focusing on their...
Md Belal Bin Heyat, A. Rehman, H. M. Zeeshan et al.· WIREs Data Mining and Knowle...· 0 citations
In recent years, natural language processing has become an important tool in healthcare for extracting useful information from unstructured clinical text such as electronic health records, physician notes, and medical literature. Deep learning has significantly improved the performance of NLP systems, enabling stronger...
Madhurima Kommuru, Swathi Thatraju, Appala Nooka Kumar Doodala· International Journal of Mac...· 0 citations
This paper conducts a comprehensive analysis of evaluation methods, deployment processes, and governance strategies for LLMs in the healthcare field, focusing on three key issues: model version drift, multilingual external validation, and prompt injection security governance.
Song-Bin Guo, Sui-Xing Zhong, Yixian Ma et al.· International Journal of Sur...· 0 citations
A scoping review of 24 PubMed-indexed studies published between 2023 and 2026 was conducted to assess current applications, benefits, limitations, and future directions of LLMs in healthcare.
Antoni Klamka, Paulina Kawalec, Kamil Bronikowski et al.· Quality in Sport· 0 citations
Current evidence indicates that LLMs have substantial potential to enhance healthcare delivery, research, and personalized medicine, but they should currently be regarded as supportive tools rather than autonomous clinical decision-makers.
Antoni Klamka, Paulina Kawalec, Kamil Bronikowski et al.· 0 citations
An engineering-oriented, end-to-end roadmap that structures the full lifecycle of clinical language model systems—from model design and domain adaptation to optimization and real-world evaluation is introduced.